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SONAR Targetspace for PACLITAXELZ-score WebGraph NB WebGraph
Targetspace hs 167 70
Targetspace hs pval0.395543175487470.85555555555556
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
KAP104 YBR017C Transportin, cytosolic karyopherin beta 2 involved in delivery of heterogeneous ... karyopherin beta 2 4 86   0
RAD3 YER171W 5- to 3- DNA helicase, involved in nucleotide excision repair and transcription;...   3 53   0.0865
NOP58 YOR310C Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesi... U3 snoRNP protein 3 127   0
ARX1 YDR101C Protein associated with the ribosomal export complex   3 102 3.5757 0.0091
BUD20 YLR074C Protein involved in bud-site selection; diploid mutants display a random budding...   3 74   0
NSA2 YER126C Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit bi... ribosome biogenesis 2 52   0
RPL14A YKL006W N-terminally acetylated protein component of the large (60S) ribosomal subunit, ... ribosomal protein L14A 2 17   0.1434
RPB5 YBR154C RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts... 25 kDa RNA polymerase subunit (common to polymerases I, II and III) 2 89   0
RPL31B YLR406C Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl3... ribosomal protein L31B (L34B) (YL28) 2 20   0.0138
RPA49 YNL248C RNA polymerase I subunit A49 RNA polymerase A 49 kDa alpha subunit 2 47 -7.6243 0.2789
CIT1 YNR001C Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloaceta... citrate synthase 2 4   0
KAP120 YPL125W Karyopherin with a role in the assembly or export of 60S ribosomal subunits karyopherin 2 22   0.0014
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains...   2 23   0
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochon... heat shock protein 78 2 39   0
CIT2 YCR005C Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloaceta... citrate synthase 2 9   0
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes; Rpn4p level...   2 19   0
RAD54 YGL163C DNA-dependent ATPase, stimulates strand exchange by modifying the topology of do...   2 10   0
RBG2 YGR173W Protein with similarity to mammalian developmentally regulated GTP-binding prote...   2 17   0
RAD26 YJR035W Protein involved in transcription-coupled repair nucleotide excision repair of U... DNA dependent ATPase|human Cockayne syndrome B gene ERCC6 homolog 2 24   0.0265
RPA190 YOR341W RNA polymerase I subunit; largest subunit of RNA polymerase I RNA polymerase I subunit 2 68   0
SAM2 YDR502C S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP...   2 23 8.2810 0
  YDR306C     2 13   0
SLD2 YKL108W Protein required for DNA replication, phosphorylated in S phase by S-phase cycli...   2 28   0
BUD31 YCR063W Protein involved in bud-site selection; diploid mutants display a random budding...   2 41   0
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; pro... ATP-binding cassette (ABC) family 2 34   0.0003
  YCR079W     2 26   0.0001
PSY2 YNL201C Nuclear protein of unknown function; deletion results in sensitivity to anticanc...   2 34   0.2578
  YBL009W     2 9   0
RPL24B YGR148C Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to ... ribosomal protein L24B (rp29) (YL21) (L30B) 2 22   0
NOC2 YOR206W Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre...   2 112   0
RSA4 YCR072C WD-repeat protein involved in ribosome biogenesis; required for maturation and e...   2 41   0
ARF2 YDL137W ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of... ADP-ribosylation factor 2 2 17   0.0246
RPL22B YFL034C-A Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22A... ribosomal protein L22B (L1c) (rp4) (YL31) 2 4   0
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golg... ADP-ribosylation factor GTPase-activating protein (ARF GAP) 2 21   0
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 2 6   0.0008
GGA2 YHR108W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 2 24   0.0005
RUD3 YOR216C Golgi matrix protein involved in the structural organization of the cis-Golgi; i...   2 11   0
NOG2 YNR053C Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus... part of a pre-60S complex 2 76   0
TWF1 YGR080W Twinfilin, highly conserved actin monomer-sequestering protein involved in regul... twinfilin A, an actin monomer sequestering protein 2 11   0.0002

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