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SONAR Targetspace for PACLITAXELZ-score WebGraph NB WebGraph
Targetspace hs 167 70
Targetspace hs pval0.395543175487470.85555555555556
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
GUT2 YIL155C Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by bot... glycerol-3-phosphate dehydrogenase 4 20   0
JID1 YPR061C Probable Hsp40p co-chaperone, has a DnaJ-like domain and appears to be involved ...   4 133   0
KAP104 YBR017C Transportin, cytosolic karyopherin beta 2 involved in delivery of heterogeneous ... karyopherin beta 2 4 92   0
SVL3 YPL032C Protein of unknown function, mutant phenotype suggests a potential role in vacuo...   3 86   0.0157
ZEO1 YOL109W Peripheral membrane protein of the plasma membrane that interacts with Mid2p; re...   3 25   0.2281
GRR1 YJR090C F-box protein component of the SCF ubiquitin-ligase complex, required for Cln1p ...   3 75   0.1118
  YDR306C     2 20   0
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates S...   2 13   0
RPB5 YBR154C RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts... 25 kDa RNA polymerase subunit (common to polymerases I, II and III) 2 97   0
HRK1 YOR267C Protein kinase implicated in activation of the plasma membrane H(+)-ATPase Pma1p... protein kinase similar to Npr1 2 92   0
TRM10 YOL093W tRNA methyltransferase, methylates the N-1 position of guanosine in tRNAs   2 34   0
ODC1 YPL134C Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarat... mitochondrial 2-oxodicarboxylate transport protein 2 28   0
YVH1 YIR026C Protein phosphatase involved in vegetative growth at low temperatures, sporulati... protein tyrosine phosphatase induced by nitrogen starvation 2 53   0.0844
MRM2 YGL136C Mitochondrial 21S rRNA methyltransferase, required for methylation of U(2791) in... 2-O-ribose methyltransferase 2 47   0
ACP1 YKL192C Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate... acyl carrier protein 2 10   0
RPA190 YOR341W RNA polymerase I subunit; largest subunit of RNA polymerase I RNA polymerase I subunit 2 94   0
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains...   2 23   0
CIT2 YCR005C Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloaceta... citrate synthase 2 23   0
RRN3 YKL125W Protein required for transcription of rDNA by RNA polymerase I; transcription fa... DNA independent RNA polymerase I transcription factor 2 18   0.0831
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochon... heat shock protein 78 2 65   0
SXM1 YDR395W Nuclear transport factor (karyopherin) involved in protein transport between the... karyopherin beta family member 2 71   0
  YMR087W     2 17   0
NDI1 YML120C NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in t... NADH:ubiquinone oxidoreductase|Type II NAD(P)H:quinone oxidoreductase 2 10 1.0584 0
NSA2 YER126C Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit bi... ribosome biogenesis 2 55   0
RSA4 YCR072C WD-repeat protein involved in ribosome biogenesis; required for maturation and e...   2 41   0
CYS3 YAL012W Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the tr... cystathionine gamma-lyase 2 100   0
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which cataly... NAD-dependent isocitrate dehydrogenase 2 114 4.9330 0.0077
CAR1 YPL111W Arginase, responsible for arginine degradation, expression responds to both indu... arginase 2 16   0
OAC1 YKL120W Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and ... oxaloacetate transport protein 2 29   0
RBG2 YGR173W Protein with similarity to mammalian developmentally regulated GTP-binding prote...   2 28   0
SPC98 YNL126W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts... gamma-tubulin complex component 2 24   0.0421
TWF1 YGR080W Twinfilin, highly conserved actin monomer-sequestering protein involved in regul... twinfilin A, an actin monomer sequestering protein 2 31   0.0002
NOC2 YOR206W Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre...   2 120   0
NOG2 YNR053C Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus... part of a pre-60S complex 2 78   0
SCL1 YGL011C Alpha subunit of the 20S core complex of the 26S proteasome involved in the degr... proteasome subunit YC7alpha/Y8 (protease yscE subunit 7) 2 81   0
RPL31B YLR406C Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl3... ribosomal protein L31B (L34B) (YL28) 2 38   0.0138
  ETG3064     2 95   0
VID24 YBR105C Peripheral membrane protein located at Vid (vacuole import and degradation) vesi... peripheral vesicle membrane protein 2 110   0

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