Home | Screening data | Screen comparisons | Search for compounds | Structure search

SONAR Targetspace for CYCLOSPORINEZ-score WebGraph NB WebGraph
Targetspace hs 172 101
Targetspace hs pval0.0503144654088050.13092550790068
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:36
Sym Orf Description Function No All Z_score hyperg
MET6 YER091C Cobalamin-independent methionine synthase, involved in amino acid biosynthesis; ... 5-methyltetrahydropteroyl triglutamate homocysteine methyltransferase|N5-methyltetrahydrofolate homocysteine methyltransferase|vitamin B12-(cobalamin)-independent methionine synthase 14 88   0
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 14 37   0
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   14 48   0
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component ... ubiquinol cytochrome C oxidoreductase subunit 6 (17 kDa) 13 60   0
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in pr... pol II transcribed genes regulator 12 80   0
EDC1 YGL222C RNA-binding protein, activates mRNA decapping directly by binding to the mRNA su...   12 28   0
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 12 107   0
RNH70 YGR276C 3- exoribonuclease, required for 5S and tRNA-Arg3 maturation ribonuclease H 12 79   0
IRS4 YKR019C Protein involved in regulation of phosphatidylinositol 4,5-bisphosphate concentr...   12 112   0.0002
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   12 109   0.0014
MDR1 YGR100W Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31... GTPase activating protein (GAP) for Ypt6 12 34   0
VPH1 YOR270C Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph... V0 sector subunit|essential for vacuolar acidification and vacuolar H-ATPase activity|vacuolar ATPase V0 domain subunit a (100 kDa)|vacuolar H-ATPase 11 123 -1.9054 0.0018
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase and is required ...   11 126   0
STV1 YMR054W Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv... 110 kDa subunit; not in vacuole membrane|vacuolar H-ATPase 11 71   0
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   11 94   NAN
MUD1 YBR119W U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing U1 snRNP A protein 11 109   0
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   10 100   0
SDS22 YKL193C Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine ph... Glc7p regulatory subunit 10 95   0
USO1 YDL058W Essential protein involved in intracellular protein transport, coiled-coil prote... integrin analogue gene 10 79   0
ASM4 YDL088C Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup17... nuclear pore complex subunit 10 94   0
SYG1 YIL047C Plasma membrane protein of unknown function; truncation and overexpression suppr... plasma membrane protein 10 46   0
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 10 91   0.0143
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   10 89   0
RAV2 YDR202C Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 dom...   10 103   0.0724
CMP2 YML057W Calcineurin A; one isoform (the other is CNA1) of the catalytic subunit of calci... calcineurin subunit A 10 46   0
DBR1 YKL149C RNA lariat debranching enzyme, involved in intron turnover; required for efficie... RNA lariat debranching enzyme 10 56   0
DCR2 YLR361C Putative phosphoesterase that functions as a dosage-dependent positive regulator...   9 77   0
  YIL039W     9 115   0
  YDR266C     9 36   0
FAR11 YNL127W Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway ...   9 104   0.012
MRL1 YPR079W Membrane protein with similarity to mammalian mannose-6-phosphate receptors, pos...   9 55   0.0846
  YOR246C     9 92   0
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   9 134   0.1295
  YGR071C     8 54   0.0364
SEC21 YNL287W Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p... PEST sequence-containing protein|non-clathrin coat protein 8 67   0
DOT5 YIL010W Nuclear thiol peroxidase which functions as an alkyl-hydroperoxide reductase dur...   8 25   0

Service provided by the Mike Tyers Laboratory