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SONAR Targetspace for PACLITAXELZ-score WebGraph NB WebGraph
Targetspace hs 167 70
Targetspace hs pval0.395543175487470.85555555555556
XgmmL File for compound download download
Stats file for targetspace download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
GUT2 YIL155C Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by bot... glycerol-3-phosphate dehydrogenase 4 10   0
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis; interacts and functio... transcription factor 3 76   0
GRR1 YJR090C F-box protein component of the SCF ubiquitin-ligase complex, required for Cln1p ...   3 42   0.1118
RRN3 YKL125W Protein required for transcription of rDNA by RNA polymerase I; transcription fa... DNA independent RNA polymerase I transcription factor 2 6   0.0831
RAD23 YEL037C Protein with ubiquitin-like N terminus, recognizes and binds damaged DNA (with R... ubiquitin-like protein 2 50 1.1069 0.0188
  ETG3064     2 46   0
AAT1 YKL106W Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloaceta... aspartate aminotransferase 2 10   0
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which cataly... NAD-dependent isocitrate dehydrogenase 2 15 4.9330 0.0077
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involv... GTP-binding protein|rho subfamily 2 26   0.1895
UPC2 YDR213W Sterol regulatory element binding protein, induces transcription of sterol trans... zinc finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type 2 24   0
SAM1 YLR180W S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP...   2 11   0.2114
RPA135 YPR010C RNA polymerase I subunit A135 RNA polymerase I subunit 2 6   0.0831
GEA1 YJR031C Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved... GDP/GTP exchange factor 2 14   0.2404
MDH2 YOL126C Cytoplasmic malate dehydrogenase, one of the three isozymes that catalyze interc... malate dehydrogenase 2 4   0.212
HST1 YOL068C NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p...   2 25   0
NDI1 YML120C NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in t... NADH:ubiquinone oxidoreductase|Type II NAD(P)H:quinone oxidoreductase 2 4 1.0584 0
OAC1 YKL120W Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and ... oxaloacetate transport protein 2 12   0
CYS3 YAL012W Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the tr... cystathionine gamma-lyase 2 61   0
CIT2 YCR005C Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloaceta... citrate synthase 2 13   0
HAP4 YKL109W Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding co... transcriptional activator protein of CYC1 (component of HAP2/HAP3 heteromer) 2 10   0.1079
ZAP1 YJL056C Zinc-regulated transcription factor, binds to zinc-responsive promoter elements ...   2 30   0
ACP1 YKL192C Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate... acyl carrier protein 2 4   0
FOB1 YDR110W Nucleolar protein required for DNA replication fork blocking and recombinational... DNA replication fork blocking protein 1 23   0.2497
  YLR168C     1 10   0.0001
MRPS8 YMR158W Mitochondrial ribosomal protein of the small subunit   1 1   0.0002
BUL1 YMR275C Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional...   1 25   0.0012
MDM38 YOL027C Mitochondrial inner membrane protein, required for K+/H+ exchange and for normal...   1 8   0.0001
ELF1 YKL160W Transcription elongation factor that contains a conserved zinc finger domain; im...   1 19 0.5319 0
RVB2 YPL235W Essential protein involved in transcription regulation; component of chromatin r... transcriptional regulator 1 20   0.0006
RVB1 YDR190C Essential protein involved in transcription regulation; component of chromatin r...   1 13   0.0232
CET1 YPL228W Beta (RNA 5--triphosphatase) subunit of the mRNA capping enzyme, a heterodimer (... RNA 5--triphosphatase|mRNA capping enzyme beta subunit (80 kDa) 1 8   0.0002
UBP2 YOR124C Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, ... ubiquitin-specific protease 1 7   0
GIC1 YHR061C Protein of unknown function involved in initiation of budding and cellular polar...   1 37   0.2862
MDM35 YKL053C-A Protein of unknown function; mutation affects mitochondrial distribution and mor...   1 6   0
BET1 YIL004C Type II membrane protein required for vesicular transport between the endoplasmi...   1 26   0.0487
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 1 2   0.2973
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 1 38   0
OLE1 YGL055W Fatty acid desaturase, required for monounsaturated fatty acid synthesis and for... delta-9-fatty acid desaturase 1 13   0.2234
GEA2 YEL022W Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved... ARF GTP/GDP exchange factor 1 9   0.0342
CMD1 YBR109C Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mito... calmodulin 1 18   0.0197

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