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SONAR Targetspace for QUINACRINE HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 85 419
Targetspace hs pval0.658940397350990.041580041580042
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
IRE1 YHR079C Serine-threonine kinase and endoribonuclease; transmembrane protein that initiat... endoribonuclease|serine-threonine kinase|transmembrane protein 9 95 -16.9881 0.0716
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golg... similar to Gcs1p and Sps18p|zinc finger protein 8 48   0.0871
GCN5 YGR252W Histone acetyltransferase, acetylates lysine 14 on histone H3; catalytic subunit... histone acetyltransferase 8 119 -6.1171 0.1175
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 8 15   0
SES1 YDR023W Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoac... serine-tRNA ligase 7 56   0
  YBR108W     7 38   0
KAR2 YJL034W ATPase involved in protein import into the ER, also acts as a chaperone to media... HSP70 family|mammalian BiP (GRP78 or HSPA5) homolog 7 58   0
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome... Shuttling protein, ATP binding cassette protein 7 74   0
TPO3 YPR156C Polyamine transport protein specific for spermine; localizes to the plasma membr...   6 5   0
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex, involved in maintaining ... histone acetyltransferase SAGA complex member|transcription factor 6 52   0
CHS1 YNL192W Chitin synthase I, requires activation from zymogenic form in order to catalyze ... chitin synthase 1 6 14   0.0067
SKP1 YDR328C Evolutionarily conserved kinetochore protein that is part of multiple protein co...   6 137   0
ADA2 YDR448W Transcription coactivator, component of the ADA and SAGA transcriptional adaptor... transcription factor 6 108   0.0003
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase...   6 83   0
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex, a histone... Ada/Gcn5 protein complex member|transcription factor 6 49   0.0004
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p, located on cyto... GDP/GTP exchange factor 5 69   0
MLF3 YNL074C Serine-rich protein of unknown function; overproduction suppresses the growth in...   5 16   0
ATG19 YOL082W Protein involved in the cytoplasm-to-vacuole targeting pathway and in autophagy,... Receptor for biosynthetic cytoplasm to vacuole targeting 5 40   0
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase, catalyzes the dephosph... phosphatidate phosphohydrolase 5 42   0
  YMR184W     5 19   0
  YNR047W     5 25   0
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p; required for recycling Golgi ... cysteine rich putative zinc finger essential for function|hydrophilic protein 5 25   0
RET1 YOR207C Second-largest subunit of RNA polymerase III, which is responsible for the trans...   5 52   0.1708
MTW1 YAL034W-A Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p...   5 50   0
  YMR295C     5 9   0
  YNL284C-A     5 19   0
  YPL257W-A     5 15   0
  YML037C     5 29   0
PRM10 YJL108C Pheromone-regulated protein, predicted to have 5 transmembrane segments   5 6   0
YAP6 YDR259C Putative basic leucine zipper (bZIP) transcription factor; overexpression increa...   5 22   0
  YDR134C     5 16   0.0796
  YML045W-A     5 16   0
  YDL186W     5 5   0
RTG3 YBL103C Basic helix-loop-helix-leucine zipper (bHLH/Zip) transcription factor that forms... phosphoprotein 5 24   0
VHS2 YIL135C Cytoplasmic protein of unknown function; identified as a high-copy suppressor of...   5 19   0
SSK1 YLR006C Cytoplasmic response regulator, part of a two-component signal transducer that m... two-component signal transducer that with Sln1p regulates osmosensing MAP kinase cascade(suppressor of sensor kinase) 5 18   0
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role   5 35   0

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