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SONAR Targetspace for QUINACRINE HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 85 419
Targetspace hs pval0.658940397350990.041580041580042
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:35
Sym Orf Description Function No All Z_score hyperg
ERG1 YGR175C Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; ... squalene monooxygenase 10 36   0
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding and autopha... vesicle coat component 9 59   0
SEC13 YLR208W Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (S... nuclear pore complex subunit|protein involved in release of transport vesicles from the ER 8 98   0
  YHR045W     8 22   0
ATF2 YGR177C Alcohol acetyltransferase, may play a role in steroid detoxification; forms vola... alcohol acetyltransferase 8 29   0.0001
SSP120 YLR250W Protein of unknown function; green fluorescent protein (GFP)-fusion protein loca...   8 11   0
ERP5 YHR110W Protein with similarity to Emp24p and Erv25p, member of the p24 family involved ... p24 protein involved in membrane trafficking 8 45   0
TPO3 YPR156C Polyamine transport protein specific for spermine; localizes to the plasma membr...   7 46   0
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome... Shuttling protein, ATP binding cassette protein 7 75   0
SES1 YDR023W Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoac... serine-tRNA ligase 7 61   0
EPT1 YHR123W sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential ... sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase 7 69   0
YSY6 YBR162W-A Protein whose expression suppresses a secretory pathway mutation in E. coli; has...   7 29   0
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase, involved in the synthes... Dol-P-Man dependent alpha(1-3) mannosyltransferase (putative) 6 79   0
SEC31 YDL195W Essential phosphoprotein component (p150) of the COPII coat of secretory pathway... COPII coat of secretory pathway vesicles component (p150) 6 51   0
GPI17 YDR434W Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase c... GPI transamidase component, human PIG-S homologue 6 24   0.0516
BIG1 YHR101C Integral membrane protein of the endoplasmic reticulum, required for normal cont...   6 63   0.0045
  YLR064W     6 34   0
MSN4 YKL062W Transcriptional activator related to Msn2p; activated in stress conditions, whic... zinc finger protein 6 64   0
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex, involved in maintaining ... histone acetyltransferase SAGA complex member|transcription factor 6 89   0
  YNL224C     6 55   0.0489
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase...   6 83   0
ERV29 YGR284C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... ER-Golgi transport vesicle protein 6 114   0.0006
  YML045W-A     5 16   0
  YMR184W     5 19   0
  YDL186W     5 19   0
ERI1 YPL096C-A Endoplasmic reticulum membrane protein that binds to and inhibits GTP-bound Ras2...   5 48   0
YVH1 YIR026C Protein phosphatase involved in vegetative growth at low temperatures, sporulati... protein tyrosine phosphatase induced by nitrogen starvation 5 53   0.1882
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 5 133   0
  YNL284C-A     5 19   0
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec1... exocyst complex component 5 58   0.1887
ADE3 YGR204W Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in singl... C1-tetrahydrofolate synthase 5 30   0
GCN4 YEL009C Transcriptional activator of amino acid biosynthetic genes in response to amino ... transcriptional activator of amino acid biosynthetic genes 5 94   0
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily, expressio... hexose transporter 5 89 -10.7626 0
SEC12 YNR026C Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein... guanine nucleotide exchange factor for Sar1p 5 51   0.0017
YAP6 YDR259C Putative basic leucine zipper (bZIP) transcription factor; overexpression increa...   5 29   0

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