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SONAR Targetspace for ESTRADIOLZ-score WebGraph NB WebGraph
Targetspace hs 370 229
Targetspace hs pval0.192857142857140.070512820512821
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 6 13   0
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 6 25   0
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   4 43   0
MDR1 YGR100W Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31... GTPase activating protein (GAP) for Ypt6 4 13   0
SGM1 YJR134C Protein of unknown function, required for wild-type growth rate on galactose and...   3 8   0.2273
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p 3 18   0.0632
ACO1 YLR304C Aconitase, required for the tricarboxylic acid (TCA) cycle and also independentl... aconitase 3 28   0
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   3 45   0
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   3 28   0.0657
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network; forms heterod...   3 14 -1.6276 0
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   3 31   0
MSB4 YOL112W GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, l...   3 11   0
YIP4 YGL198W Protein that interacts with Rab GTPases; computational analysis of large-scale p...   3 26   0
YOP1 YPR028W Membrane protein that interacts with Yip1p to mediate membrane traffic; overexpr...   3 17   0
MRS6 YOR370C Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is... rab geranylgeranyltransferase regulatory subunit 3 22   0.0025
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor, contains... polyadenylation factor subunit 2 32   0
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex, involved in proper assem... histone acetyltransferase SAGA complex member|transcription factor 2 70   0.2555
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiati... TATA-binding protein-associated-factor 2 102   0.0001
SGF73 YGL066W Probable 73 kDa subunit of SAGA histone acetyltransferase complex Probable 73KkDa Subunit of SAGA histone acetyltransferase complex 2 57   0.2816
NGG1 YDR176W Transcriptional regulator involved in glucose repression of Gal4p-regulated gene... genetic and mutant analyses suggest that Ngg1p (Ada3p) is part of two transcriptional adaptor/HAT (histone acetyltransferase complexes, the 0.8 MD ADA complex and the 1.8 MD SAGA complex|transcription factor 2 65   0.0707
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II tran...   2 84   0.0423
SSU72 YNL222W Transcription/RNA-processing factor that associates with TFIIB and cleavage/poly...   2 40   0.0001
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor, may have a...   2 14   0.1254
PTA1 YAL043C Subunit of holo-CPF, a multiprotein complex and functional homolog of mammalian ... cleavage factor II (CF II) component|polyadenylation factor I (PF I) 2 60   0.0203
PTI1 YGR156W Pta1p Interacting protein   2 35   0.2839
MPE1 YKL059C Essential conserved subunit of CPF (cleavage and polyadenylation factor), plays ...   2 36   0
PFS2 YNL317W Integral subunit of the pre-mRNA cleavage and polyadenylation factor (CPF) compl... polyadenylation factor I (PF I) 2 43   0
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with aci... ATM/Mec1/TOR1/TOR2-related|NuA4 complex component 2 93   0.0001
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II tran... TFIID subunit 2 74   0.1239
UBP8 YMR223W Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyl...   2 49 -1.0766 0.241
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   2 12   0.0322
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   2 22   0
YIF1 YNL263C Integral membrane protein required for the fusion of ER-derived COPII transport ...   2 39   0
YSH1 YLR277C Putative endonuclease, subunit of the mRNA cleavage and polyadenylation specific... cleavage factor II (CF II) component|polyadenylation factor I (PF I) 1 42   0
RPL2A YFR031C-A Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and ... ribosomal protein L2A (L5A) (rp8) (YL6) 1 126   0
PAP1 YKR002W Poly(A) polymerase, one of three factors required for mRNA 3--end polyadenylatio... poly(A) polymerase 1 46   0.002
VAM6 YDL077C Vacuolar protein that plays a critical role in the tethering steps of vacuolar m...   1 39   0.0499
CFT1 YDR301W RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in... 150 kDa protein associated with polyadenylation factor 1 (PF I)|cleavage factor II (CF II) component 1 47   0
PEX14 YGL153W Peroxisomal membrane protein that is a central component of the peroxisomal prot... peroxin 1 44   0.1608
VPS33 YLR396C ATP-binding protein that is a subunit of the homotypic vacuole fusion and vacuol...   1 35   0.14

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