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SONAR Targetspace for ESTRADIOLZ-score WebGraph NB WebGraph
Targetspace hs 370 229
Targetspace hs pval0.192857142857140.070512820512821
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component ... ubiquinol cytochrome C oxidoreductase subunit 6 (17 kDa) 8 60   0
SYG1 YIL047C Plasma membrane protein of unknown function; truncation and overexpression suppr... plasma membrane protein 7 46   0
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   6 48   0.0005
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 6 107   0
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase and is required ...   5 126   0
RNH70 YGR276C 3- exoribonuclease, required for 5S and tRNA-Arg3 maturation ribonuclease H 5 79   0
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 5 37   0
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   5 94   0
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor, contains... polyadenylation factor subunit 5 35   0
  YGR071C     5 54   0.1775
  YOR246C     5 92   0
DBR1 YKL149C RNA lariat debranching enzyme, involved in intron turnover; required for efficie... RNA lariat debranching enzyme 5 56   0.001
MUD1 YBR119W U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing U1 snRNP A protein 4 109   0.0077
EDC1 YGL222C RNA-binding protein, activates mRNA decapping directly by binding to the mRNA su...   4 28   0.065
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 4 91   0
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   4 112   0.1764
NAM2 YLR382C Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of seve... LeuRS|leucine-tRNA ligase 4 26   0
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   4 134   0.0683
SDS22 YKL193C Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine ph... Glc7p regulatory subunit 4 95   0
ASM4 YDL088C Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup17... nuclear pore complex subunit 4 94   0
  ETG9627     3 21   0
RAV2 YDR202C Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 dom...   3 103   0.0535
MRS6 YOR370C Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is... rab geranylgeranyltransferase regulatory subunit 3 35   0.0025
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 3 72   0
OXR1 YPL196W Protein of unknown function required for normal levels of resistance to oxidativ...   3 8   0.0904
  YPR084W     3 27   0.0001
  YDL133W     3 126   0
  YDR107C     3 15   0.0447
DSS4 YPR017C Nucleotide release factor functioning in the post-Golgi secretory pathway, requi... GDP dissociation factor for Sec4p 3 34   0.0751
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   3 100   0.147
RAD30 YDR419W DNA polymerase eta, involved in the predominantly error-free bypass replication ... DNA polymerase eta 3 88   0.0005
SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to... v-SNARE 3 16   0.1012
DIS3 YOL021C Nucleolar exosome component, involved in rRNA processing and RNA degradation, bi... 3--5- exoribonuclease complex subunit 3 73   0
DOT5 YIL010W Nuclear thiol peroxidase which functions as an alkyl-hydroperoxide reductase dur...   3 25   0
ENT4 YLL038C Protein of unknown function, contains an N-terminal epsin-like domain   3 63   0.208
  YIL042C     3 19   0
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in tr... v-SNARE 3 62   0.0538
AKR2 YOR034C Ankyrin repeat-containing protein similar to Akr1p; member of a family of putati...   3 18   0
SGM1 YJR134C Protein of unknown function, required for wild-type growth rate on galactose and...   3 42   0.2273
YRM1 YOR172W Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multi... zinc finger transcription factor 3 19   0.0744

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