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SONAR Targetspace for DONEPEZIL HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 247 122
Targetspace hs pval0.0245398773006130.36885245901639
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:29
Sym Orf Description Function No All Z_score hyperg
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   10 89   0
NHX1 YDR456W Endosomal Na+/H+ exchanger, required for intracellular sequestration of Na+; req... Na+/H+ exchanger 10 84   0
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   10 96   NAN
MRL1 YPR079W Membrane protein with similarity to mammalian mannose-6-phosphate receptors, pos...   9 55   0.0846
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxy...   9 86   0.0004
GEF1 YJR040W Chloride channel localized to late- or post-Golgi vesicles, involved in iron met... transport protein involved in intracellular iron metabolism (putative) 8 83   0
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase and is required ... type 2A-related protein phosphatase 8 104   0
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   8 100   0.0002
DCR2 YLR361C Putative phosphoesterase that functions as a dosage-dependent positive regulator...   7 77   0
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   7 94   NAN
EDC1 YGL222C RNA-binding protein, activates mRNA decapping directly by binding to the mRNA su...   7 28   0.0013
CAF40 YNL288W Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling...   7 105   0.1232
  YEL043W     7 70   0
  YMR003W     7 70   0
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 6 37   0
TEC1 YBR083W Transcription factor required for full Ty1 epxression, Ty1-mediated gene activat... TEA/ATTS DNA-binding domain family transcription factor 6 72   0.0266
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   6 48   0.0005
RNH201 YNL072W Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment s...   6 58   0.1756
CSI1 YMR025W Subunit of the Cop9 signalosome, which is required for deneddylation, or removal... Interactor with COP9 signalosome (CSN) complex 6 43   0
ARF2 YDL137W ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of... ADP-ribosylation factor 2 6 79   0.1675
MUD1 YBR119W U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing U1 snRNP A protein 6 109   0.0001
UBC8 YEL012W Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediat... ubiquitin-conjugating enzyme 6 70   0
FAR11 YNL127W Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway ...   6 104   0.1114
NAM2 YLR382C Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of seve... LeuRS|leucine-tRNA ligase 6 26   0
  YOR112W     6 34   0.1221
PEP8 YJL053W Vacuolar protein sorting protein that forms part of the multimeric membrane-asso... vacuolar protein similar to mouse gene H<beta>58 6 95   0
FAR10 YLR238W Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway ...   6 117   0
SED5 YLR026C cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and t... syntaxin family 6 96   0
YPT10 YBR264C GTP binding protein that contains the PEST signal sequence specific for proteoly...   6 37   0

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