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SONAR Targetspace for SIMVASTATINZ-score WebGraph NB WebGraph
Targetspace hs 98 102
Targetspace hs pval0.187203791469190.3801652892562
XgmmL File for compound download download
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Targetspace Analysis download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3, which is involved...   6 97   0
VRG4 YGL225W Golgi GDP-mannose transporter; regulates Golgi function and glycosylation in Gol...   4 46   0.0134
DOP1 YDR141C Protein of unknown function, essential for viability, involved in establishing c...   4 40   0.0152
MET6 YER091C Cobalamin-independent methionine synthase, involved in amino acid biosynthesis; ... 5-methyltetrahydropteroyl triglutamate homocysteine methyltransferase|N5-methyltetrahydrofolate homocysteine methyltransferase|vitamin B12-(cobalamin)-independent methionine synthase 3 88   0.0931
  YMR031C     3 55   0
FAS2 YPL231W Alpha subunit of fatty acid synthetase, which catalyzes the synthesis of long-ch... fatty acid synthase alpha subunit 3 35   0
LAG1 YHL003C Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-co...   3 48   0.1246
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 3 98   0
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing, interacts with Si...   3 51   0
CDC39 YCR093W Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA l... transcriptional regulator 3 78   0.0063
SVP26 YHR181W Integral membrane protein of the early Golgi apparatus, may function to promote ... integral membrane protein 3 69   0
RGT1 YKL038W Glucose-responsive transcription factor that regulates expression of several glu... transcriptional activator|transcriptional repressor 2 45   0
FET3 YMR058W Ferro-O2-oxidoreductase required for high-affinity iron uptake and involved in m... multicopper oxidase 2 93 -0.9781 0.0002
  YMR187C     2 13   0
TRM3 YDL112W 2--O-ribose methyltransferase, catalyzes the ribose methylation of the guanosine... tRNA (Gm18) ribose methylase 2 61   0
AQY2 YLL052C Water channel that mediates the transport of water across cell membranes, only e... MIP family member|aquaporin (putative) 2 14   0.0204
GLK1 YCL040W Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irrever... glucokinase 2 24   0.2679
  YFL040W     2 15   0
  YJL206C     2 40   0
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   2 96   0
NSL1 YPL233W Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p... Protein required for cell viability 2 79   0
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   2 94   0
HEM2 YGL040C Delta-aminolevulinate dehydratase, a homo-octameric enzyme, catalyzes the conver... delta-aminolevulinate dehydratase (porphobilinogen synthase) 2 41   0
FAR7 YFR008W Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway ...   2 91   0.1434
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase, aminoacylates tryptophanyl-tRNA tryptophan-tRNA ligase 2 10   0
GEA2 YEL022W Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved... ARF GTP/GDP exchange factor 2 38   0.0882
MPD2 YOL088C Member of the protein disulfide isomerase (PDI) family, exhibits chaperone activ... protein disulfide isomerase related protein 2 24   0.1079
RPL9A YGL147C Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9... ribosomal protein L9A (L8A) (rp24) (YL11) 2 102   0.0575
HMG1 YML075C One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-Co... 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase isozyme 2 108   0.0479
  YOR285W     2 38   0
  YPR114W     2 19   0
HIS4 YCL030C Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphorib... histidinol dehydrogenase 2 18   0.0195
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase, catalyzes the interconversion of glu... glucose-6-phosphate isomerase|phosphoglucose isomerase 2 29   0
SPP1 YPL138C Subunit of COMPASS (Set1C), a complex which methylates histone H3 on lysine 4 an... compass (complex proteins associated with Set1p) component 2 101   0.2671
  YKL063C     2 28   0
  YER113C     2 22   0
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase, required for ...   2 114   0
  YOL092W     2 42   0

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