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SONAR Targetspace for SIMVASTATINZ-score WebGraph NB WebGraph
Targetspace hs 98 102
Targetspace hs pval0.187203791469190.3801652892562
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg⇓
PRI1 YIR008C Subunit of DNA primase, which is required for DNA synthesis and double-strand br... DNA primase p48 polypeptide 1 13   0.3823
PTH1 YHR189W One of two (see also PTH2) mitochondrially-localized peptidyl-tRNA hydrolases; d...   1 4   0.3795
GAL11 YOL051W Component of the Mediator complex; interacts with RNA polymerase II and the gene... RNA polymerase II holoenzyme complex component|positive and negative transcriptional regulator of genes involved in mating-type specialization 1 46   0.3771
RMD8 YFR048W Cytosolic protein required for sporulation   1 5   0.3627
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps2... ribosomal protein S29B (S36B) (YS29) 1 6   0.3363
MSY1 YPL097W Mitochondrial tyrosyl-tRNA synthetase tyrosine-tRNA ligase 1 3   0.3166
PBP1 YGR178C Protein interacting with poly(A)-binding protein Pab1p; likely involved in contr...   1 8   0.3115
MOT3 YMR070W Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repres... 2 Cys2-His2 zinc fingers at c-terminus, glutamine and asparagine rich 1 15   0.3023
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5- cap st...   1 21   0.2955
SPT5 YML010W Protein that forms a complex with Spt4p and mediates both activation and inhibit... transcription factor 2 33   0.2753
SPP1 YPL138C Subunit of COMPASS (Set1C), a complex which methylates histone H3 on lysine 4 an... compass (complex proteins associated with Set1p) component 2 35   0.2671
RPB2 YOR151C RNA polymerase II second largest subunit B150, part of central core; similar to ...   1 19   0.2649
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing, required for...   1 4   0.2649
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and ... ribosomal protein S8A (S14A) (rp19) (YS9) 1 8   0.2601
SPT6 YGR116W Essential protein that interacts with histones and is involved in nucleosome dis... interacts with histones, primarily histone H3, possesses nucleosome assembly activity|transcriptional regulator 1 33   0.2408
ATP11 YNL315C Molecular chaperone, required for the assembly of alpha and beta subunits into t...   1 7   0.18
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily, required for nonsense mediate... helicase (putative) 1 38   0.1715
  YNL086W     1 8   0.169
CTR9 YOL145C Component of the Paf1p complex, which is a large complex that binds to and modul...   2 28   0.1107
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   2 25   0.1029
CHS2 YBR038W Chitin synthase II, requires activation from zymogenic form in order to catalyze... chitin synthase 2 2 2   0.0831
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex; type II membrane protein; ...   1 9   0.0675
CDC3 YLR314C Component of the septin ring of the mother-bud neck that is required for cytokin... septin 1 7   0.0675
MST1 YKL194C Mitochondrial threonyl-tRNA synthetase   1 4   0.0675
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-facto... farnesyltransferase beta subunit 1 7   0.0675
SLM4 YBR077C Component of the EGO complex, which is involved in the regulation of microautoph...   1 10   0.0675
BGL2 YGR282C Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall m... cell wall endo-beta-1,3-glucanase 1 5   0.0596
YTA12 YMR089C Component, with Afg3p, of the mitochondrial inner membrane m-AAA protease that m... ATPase|CDC48/PAS1/SEC18 (AAA) family 2 16   0.0582
DHH1 YDL160C Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct...   2 46   0.0456
CDC36 YDL165W Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA l... transcriptional regulator 1 14   0.0131
CDC39 YCR093W Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA l... transcriptional regulator 3 23   0.0063
CAK1 YFL029C Cyclin-dependent kinase-activating kinase required for passage through the cell ... cyclin-dependent kinase-activating kinase 2 24   0.0026
CWH43 YCR017C Putative sensor/transporter protein involved in cell wall biogenesis; contains 1...   1 48   0.0007
BUG1 YDL099W Protein of unknown function; green fluorescent protein (GFP)-fusion protein loca...   2 26   0.0002
  ETG672     1 19   0
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golg... ADP-ribosylation factor GTPase-activating protein (ARF GAP) 2 95   0
GDA1 YEL042W Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-m... guanosine diphosphatase of Golgi membrane 2 33   0
NHP6A YPR052C High-mobility group non-histone chromatin protein, functionally redundant with N... 11 kDa nonhistone chromosomal protein 1 49   0
PDR10 YOR328W ABC (ATP-binding cassette) membrane pump involved in the pleiotropic drug resist... ABC transporter (putative)|highly similar to Pdr5p 1 8   0
SCW10 YMR305C Cell wall protein with similarity to glucanases; may play a role in conjugation ... soluble cell wall protein 1 8   0

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