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SONAR Targetspace for ESTRADIOLZ-score WebGraph NB WebGraph
Targetspace hs 370 229
Targetspace hs pval0.192857142857140.070512820512821
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   6 12   0.0049
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 5 56   0.0001
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   4 41   0
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   4 42 -2.2253 0
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   4 32   0
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   3 30   0.1228
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in tr... v-SNARE 3 14   0.0538
TEF4 YKL081W Translation elongation factor EF-1 gamma translation elongation factor EF-1gamma 3 15   0.223
SEC18 YBR080C ATPase required for the release of Sec17p during the -priming- step in homotypic... ATPase|NSF|protein involved in protein transport between ER and Golgi 3 33   0.2144
GMH1 YKR030W Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; requ...   3 5   0.0261
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts p... phosphatidylserine decarboxylase 3 45   0.0619
RSN1 YMR266W Membrane protein of unknown function; overexpression suppresses NaCl sensitivity...   3 10   0.1388
  YMR010W     3 4   0
EMP70 YLR083C Protein whose 24kDa cleavage product is found in endosome-enriched membrane frac...   3 7   0.2319
IMH1 YLR309C Protein involved in vesicular transport, mediates transport between an endosomal...   3 4   0
  YIL039W     3 65   0
INO4 YOL108C Transcription factor required for derepression of inositol-choline-regulated gen... basic helix-loop-helix (bHLH) protein 3 10   0
MAF1 YDR005C Negative regulator of RNA polymerase III; component of several signaling pathway...   3 50   0.064
  YDR107C     3 5   0.0447
SFT2 YBL102W Non-essential tetra-spanning membrane protein found mostly in the late Golgi, ca...   3 8   0
USO1 YDL058W Essential protein involved in intracellular protein transport, coiled-coil prote... integrin analogue gene 3 21   0.0221
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   3 73   0.0019
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required...   3 5   0
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   3 8   0.1301
RAV2 YDR202C Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 dom...   3 7   0.0535
RIM15 YFL033C Glucose-repressible protein kinase involved in signal transduction during cell p... trehalose-associated protein kinase related to S. pombe cek1+ 3 20   0.0384
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   3 20   0.034
SBH1 YER087C-B Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involv... Sbh2p homolog 3 11   0
  YEL043W     3 4   0
  YDR266C     3 6   0
SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to... v-SNARE 3 9   0.1012
ENT4 YLL038C Protein of unknown function, contains an N-terminal epsin-like domain   3 4   0.208
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 3 67 -1.4394 0
DSS4 YPR017C Nucleotide release factor functioning in the post-Golgi secretory pathway, requi... GDP dissociation factor for Sec4p 3 14   0.0751
OXR1 YPL196W Protein of unknown function required for normal levels of resistance to oxidativ...   3 2   0.0904
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   3 22   0.0657
COG1 YGL223C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   3 26   0.0204
NTO1 YPR031W Component of the histone acetyltransferase complex HAT complex component 3 10   0.0001
  YPL105C     3 2   0
GAP1 YKR039W General amino acid permease; localization to the plasma membrane is regulated by... general amino acid permease 3 41   0

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