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SONAR Targetspace for ESTRADIOLZ-score WebGraph NB WebGraph
Targetspace hs 370 229
Targetspace hs pval0.192857142857140.070512820512821
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score⇑ hyperg
  ETG9627     3 21   0
  YDL133W     3 126   0
  YDR107C     3 15   0.0447
  YGR071C     5 54   0.1775
  YIL042C     3 19   0
  YOR246C     5 92   0
  YPR084W     3 27   0.0001
AKR2 YOR034C Ankyrin repeat-containing protein similar to Akr1p; member of a family of putati...   3 18   0
ASM4 YDL088C Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup17... nuclear pore complex subunit 4 94   0
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   5 94   0
DBR1 YKL149C RNA lariat debranching enzyme, involved in intron turnover; required for efficie... RNA lariat debranching enzyme 5 56   0.001
DIS3 YOL021C Nucleolar exosome component, involved in rRNA processing and RNA degradation, bi... 3--5- exoribonuclease complex subunit 3 73   0
DOT5 YIL010W Nuclear thiol peroxidase which functions as an alkyl-hydroperoxide reductase dur...   3 25   0
DSS4 YPR017C Nucleotide release factor functioning in the post-Golgi secretory pathway, requi... GDP dissociation factor for Sec4p 3 34   0.0751
EDC1 YGL222C RNA-binding protein, activates mRNA decapping directly by binding to the mRNA su...   4 28   0.065
ENT4 YLL038C Protein of unknown function, contains an N-terminal epsin-like domain   3 63   0.208
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   4 112   0.1764
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 5 37   0
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 3 72   0
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 6 107   0
MRS6 YOR370C Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is... rab geranylgeranyltransferase regulatory subunit 3 35   0.0025
MUD1 YBR119W U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing U1 snRNP A protein 4 109   0.0077
NAM2 YLR382C Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of seve... LeuRS|leucine-tRNA ligase 4 26   0
OXR1 YPL196W Protein of unknown function required for normal levels of resistance to oxidativ...   3 8   0.0904
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component ... ubiquinol cytochrome C oxidoreductase subunit 6 (17 kDa) 8 60   0
RAD30 YDR419W DNA polymerase eta, involved in the predominantly error-free bypass replication ... DNA polymerase eta 3 88   0.0005
RAV2 YDR202C Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 dom...   3 103   0.0535
RNH70 YGR276C 3- exoribonuclease, required for 5S and tRNA-Arg3 maturation ribonuclease H 5 79   0
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase and is required ...   5 126   0
SDS22 YKL193C Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine ph... Glc7p regulatory subunit 4 95   0
SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to... v-SNARE 3 16   0.1012
SGM1 YJR134C Protein of unknown function, required for wild-type growth rate on galactose and...   3 42   0.2273
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   3 100   0.147
SYG1 YIL047C Plasma membrane protein of unknown function; truncation and overexpression suppr... plasma membrane protein 7 46   0
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   4 134   0.0683
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   6 48   0.0005
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in tr... v-SNARE 3 62   0.0538
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 4 91   0
YRM1 YOR172W Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multi... zinc finger transcription factor 3 19   0.0744
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor, contains... polyadenylation factor subunit 5 35   0

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