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SONAR Targetspace for CLOMIPRAMINE HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 249 325
Targetspace hs pval0.255639097744360.26515151515152
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
BRE1 YDL074C E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, r...   5 27 -4.6784 0
ISW1 YBR245C Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodelin... ATPase component of a four subunit chromatin remodeling complex 4 66   0.1698
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA ... DNA polymerase delta binding protein 3 73   0.2199
SPC98 YNL126W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts... gamma-tubulin complex component 3 15   0.0047
UBP14 YBR058C Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin ... ubiquitin-specific protease 3 17   0.0001
TOF2 YKR010C Nonessential mitochondrial protein of unknown function with sequence similarity ...   3 28   0.1213
RPG1 YBR079C Subunit of the core complex of translation initiation factor 3(eIF3), essential ... translation initiation factor eIF3 subunit 3 88   0
AKL1 YBR059C Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; ...   3 97   0
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis, forms a complex wit... human GTBP protein homolog 3 30   0
PRE10 YOR362C 20S proteasome alpha-type subunit proteasome component YC1 (protease yscE subunit 1) 3 58   0
TPD3 YAL016W Regulatory subunit A of the heterotrimeric protein phosphatase 2A, which also co... protein phosphatase 2A regulatory subunit A 3 49   0
SWD2 YKL018W Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lys 4 and... compass (complex proteins associated with Set1p) component 3 62   0.0045
CHD1 YER164W Nucleosome remodeling factor that functions in regulation of transcription elong... transcriptional regulator 3 62   0.0006
ACF2 YLR144C Intracellular beta-1,3-endoglucanase, expression is induced during sporulation; ...   2 18   0
CBK1 YNL161W Serine/threonine protein kinase that regulates cell morphogenesis pathways; invo... serine/threonine protein kinase 2 57   0.1429
CNM67 YNL225C Component of the spindle pole body outer plaque; required for spindle orientatio...   2 29   0.0026
RTG2 YGL252C Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p...   2 34   0.087
MSH2 YOL090W Protein that forms heterodimers, with Msh3p and Msh6p, that bind to DNA mismatch... mutS homolog 2 37   0.0174
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of g...   2 7   0.0016
KIN4 YOR233W Kinase that acts by inhibiting the mitotic exit network (MEN) when the spindle p... protein kinase 2 35   0
MSH3 YCR092C Mismatch repair protein, forms dimers with Msh2p that mediate repair of insertio... forms a complex with Msh2p to repair insertion-deletion mispairs; redundant with Pms3/Msh6p in repair of insertion-deletion mispairs|mutS homolog 2 11   0.08
GYP5 YPL249C GTPase-activating protein (GAP) for yeast Rab family members, involved in ER to ... GTPase-activating protein 2 14   0
SNT1 YCR033W Subunit of the Set3C deacetylase complex; putative DNA-binding protein   2 20   0
MSS116 YDR194C DEAD-box protein required for efficient splicing of mitochondrial Group I and II... RNA helicase DEAD box 2 17   0.0225
FIR1 YER032W Protein involved in 3- mRNA processing, interacts with Ref2p; potential Cdc28p s... participant in 3- mRNA processing (putative) 2 26   0.0959
MGM101 YJR144W Protein involved in mitochondrial genome maintenance; component of the mitochond... mitochondrial nucleoid protein 2 21   0.0296
RFA3 YJL173C Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserv... replication factor-A subunit 3 2 37   0
TAO3 YIL129C Protein involved in cell morphogenesis and proliferation, associated with protei...   2 11   0.0138
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts... gamma-tubulin complex component 2 15   0
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 2 9   0.2568
YBP2 YGL060W Protein with a role in resistance to oxidative stress; has similarity to Ybp1p, ...   2 26   0.2417
RPC82 YPR190C RNA polymerase III subunit C82 82 kDa subunit of RNA polymerase III (C) 2 45   0
  YMR233W     2 9   0
  YFR011C     2 3   0
FOB1 YDR110W Nucleolar protein required for DNA replication fork blocking and recombinational... DNA replication fork blocking protein 2 34   0.2812
IOC3 YFR013W Member of a complex (Isw1a) with Isw1p that has nucleosome-stimulated ATPase act...   2 21   0.0004
RUP1 YOR138C Protein involved in regulation of Rsp5p, which is an essential HECT ubiquitin li...   2 13   0
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochon... heat shock protein 78 2 39   0
ABF2 YMR072W Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and ... HMG-1 homolog 2 45   0
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope, connects the nuclear p... colied-coil protein (putative), similar to myosin and TPR 2 21   0

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