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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
NHA1 YLR138W Na+/H+ antiporter involved in sodium and potassium efflux through the plasma mem...   6 8   0
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 6 38   0
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 6 13   0
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane with two pore domains... outward-rectifier potassium channel 6 3   0.0006
HOT1 YMR172W Transcription factor required for the transient induction of glycerol biosynthet... nuclear protein 6 16   0
SMP1 YBR182C Putative transcription factor involved in regulating the response to osmotic str...   6 11   0
RCK2 YLR248W Protein kinase involved in the response to oxidative and osmotic stress; identif...   5 48   0
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 5 13   0
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   5 16   0
CDC37 YDR168W Essential Hsp90p co-chaperone; necessary for passage through the START phase of ...   3 40   0
HSL1 YKL101W Nim1p-related protein kinase that regulates the morphogenesis and septin checkpo... serine-threonine kinase 3 105   0.2202
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interact... histone acetyltransferase SAGA complex member|transcription factor 3 46 -0.6760 0
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   3 31   0.0005
KIN28 YDL108W Serine/threonine protein kinase, subunit of the transcription factor TFIIH; invo...   3 56   0
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spin... ubiquitin-like protein 3 37   0.0108
HRP1 YOL123W Subunit of cleavage factor I, a five-subunit complex required for the cleavage a... cleavage and polyadenylation factor CF I component involved in pre-mRNA 3--end processing 3 45   0.0556
  YAR010C     3 20   0
CDC7 YDL017W DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and re... Cdc7p-Dbf4p kinase complex catalytic subunit 3 53   0.0853
TEF4 YKL081W Translation elongation factor EF-1 gamma translation elongation factor EF-1gamma 3 58   0.223
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 3 15   0.0005
SIN4 YNL236W Subunit of the Mediator complex; interacts with the RNA polymerase II holoenzyme... RNA polymerase II holoenzyme/mediator subunit 3 64   0.0297
VID21 YDR359C Component of the NuA4 histone acetyltransferase complex   3 39   0
STE7 YDL159W Signal transducing MAP kinase kinase involved in pheromone response, where it ph... MAP kinase kinase (MEK) 3 29   0
DPB2 YPR175W Second largest subunit of DNA polymerase II (DNA polymerase epsilon), required f... DNA polymerase epsilon subunit B 3 53   0
STE50 YCL032W Protein involved in mating response, invasive/filamentous growth, and osmotolera... contains SAM (sterile alpha motif) 3 32   0
RPL42A YNL162W Protein component of the large (60S) ribosomal subunit, identical to Rpl42Bp and... ribosomal protein L42A (YL27) (L41A) 3 12   0
RSC9 YML127W One of 15 subunits of the -Remodel the Structure of Chromatin- (RSC) complex; DN...   3 34   0.0021
SPT4 YGR063C Protein that forms a complex with Spt5p and mediates both activation and inhibit... transcriptional regulator|zinc finger protein 3 37   0.0103
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to ... subunit of the GINS complex 3 17   0
ASK10 YGR097W Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxi... transcriptional activator of the SKN7 mediated -two-component- regulatory system 3 36   0.1096
CDC45 YLR103C DNA replication initiation factor; recruited to MCM pre-RC complexes at replicat... chromosomal DNA replication initiation protein 3 35   0.1509
NSR1 YGR159C Nucleolar protein that binds nuclear localization sequences, required for pre-rR... nuclear localization sequence binding protein 2 44   0
NMD5 YJR132W Karyopherin, a carrier protein involved in nuclear import of proteins; importin ... Upf1p interacting protein|importin beta homolog Kap119p 2 31   0
SHO1 YER118C Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP... transmembrane osmosensor 2 60   0.001
  YPR115W     2 38   0
  YGR058W     2 12   0.0029
DST1 YGL043W General transcription elongation factor TFIIS, enables RNA polymerase II to read... RNA polymerase II elongation factor|Transcription elongation factor S-II (TFIIS)|transcription elongation factor 2 38   0.0331
PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 2 8   0
RPD3 YNL330C Histone deacetylase; regulates transcription and silencing histone deacetylase 1 62   0.0016
THP1 YOL072W Nuclear pore-associated protein, forms a complex with Sac3p that is involved in ...   1 17   0

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