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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
RVB1 YDR190C Essential protein involved in transcription regulation; component of chromatin r...   8 101   0.083
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling, component of chr... actin related protein 8 79   0
SWC4 YGR002C Protein of unknown function, component of the Swr1p complex that incorporates Ht...   6 49   0
BDF1 YLR399C Protein involved in transcription initiation at TATA-containing promoters; assoc...   6 47   0.0094
YAF9 YNL107W Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 compl...   6 54   0
VPS71 YML041C Protein of unknown function, component of the Swr1p complex that incorporates Ht...   6 28   0
VPS72 YDR485C Protein of unknown function, component of the Swr1p complex that incorporates Ht...   5 26   0
SWC3 YAL011W Protein of unknown function, component of the Swr1p complex that incorporates Ht...   5 30   0
PEP3 YLR148W Vacuolar peripheral membrane protein that promotes vesicular docking/fusion reac... vacuolar membrane protein 4 33   0.0001
CDC45 YLR103C DNA replication initiation factor; recruited to MCM pre-RC complexes at replicat... chromosomal DNA replication initiation protein 4 35   0.0582
CSM3 YMR048W Protein required for accurate chromosome segregation during meiosis   4 29   0
ARP3 YJR065C Essential component of the Arp2/3 complex, which is a highly conserved actin nuc...   4 36   0
VPS41 YDR080W Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and ...   4 36   0.2065
YPT7 YML001W GTPase; GTP-binding protein of the rab family; required for homotypic fusion eve... GTP-binding protein|rab family 4 33   0.0143
VPS5 YOR069W Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/lat... simialr to sorting nexin I 4 18 0.4862 0.0126
POL2 YNL262W Catalytic subunit of DNA polymerase epsilon, one of the major chromosomal DNA re... DNA polymerase II 3 42   0
SWC7 YLR385C Protein of unknown function, component of the Swr1p complex that incorporates Ht...   3 23   0.0029
ARP6 YLR085C Nuclear actin-related protein involved in chromatin remodeling, component of chr...   3 24   0
VPS33 YLR396C ATP-binding protein that is a subunit of the homotypic vacuole fusion and vacuol...   3 35   0.0004
MED8 YBR193C Subunit of the RNA polymerase II mediator complex; associates with core polymera... RNA polymerase II holoenzyme/mediator subunit 3 60   0.0012
CHS3 YBR023C Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to c... chitin synthase 3 3 19 -12.3728 0
HTZ1 YOL012C Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 compl... evolutionarily conserved member of the histone H2A F/Z family of histone variants 3 87 -1.6661 0
CMK2 YOL016C Calmodulin-dependent protein kinase; may play a role in stress response, many CA... calmodulin-dependent protein kinase 3 70   0
VAM6 YDL077C Vacuolar protein that plays a critical role in the tethering steps of vacuolar m...   3 39   0.1801
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); fu... clathrin assembly complex AP-3 adaptin component delta-like subunit 3 24   0
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two ... interacts with two t-SNARES, Sed5p and Pep12p|v-SNARE 3 39   0.0008
VAM7 YGL212W Component of the vacuole SNARE complex involved in vacuolar morphogenesis; SNAP-... heptad repeat motif|hydrophilic protein 3 44   0.0818
VPS16 YPL045W Subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) compl...   3 25   0.0139
RAD4 YER162C Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide ex...   3 30   0.0823
PEP5 YMR231W Peripheral vacuolar membrane protein required for protein trafficking and vacuol... Zn-finger protein (putative) 3 28 -51.5880 0.0009
DDI1 YER143W DNA damage-inducible v-SNARE binding protein, contains a ubiquitin-associated (U...   3 24   0.0003
DRS2 YAL026C Integral membrane Ca(2+)-ATPase involved in aminophospholipid translocation; req... P-type ATPase, potential aminophospholipid translocase 2 29 -39.5876 0.2288
HSF1 YGL073W Trimeric heat shock transcription factor, activates multiple genes in response t... heat shock transcription factor 2 18   0.0022
NAS2 YIL007C Protein with similarity to the p27 subunit of mammalian proteasome modulator; no...   2 24   0
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   2 5   0
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubi...   2 15   0.1959
VPS8 YAL002W Membrane-associated hydrophilic protein that interacts with the small GTPase, Vp... membrane-associated hydrophilic protein which contains a C-terminal cysteine-rich region that conforms to the H2 variant of the RING finger Zn2+ binding motif 2 19   0.0027
TOP1 YOL006C Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleavin... topoisomerase I 2 47 0.0036 0.0252
DOP1 YDR141C Protein of unknown function, essential for viability, involved in establishing c...   2 16   0.1881

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