Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
IRE1 YHR079C Serine-threonine kinase and endoribonuclease; transmembrane protein that initiat... endoribonuclease|serine-threonine kinase|transmembrane protein 8 95 7.8388 0.111
GCN5 YGR252W Histone acetyltransferase, acetylates lysine 14 on histone H3; catalytic subunit... histone acetyltransferase 7 119 2.9512 0.1559
KAR2 YJL034W ATPase involved in protein import into the ER, also acts as a chaperone to media... HSP70 family|mammalian BiP (GRP78 or HSPA5) homolog 6 58   0
AQR1 YNL065W Plasma membrane transporter of the major facilitator superfamily that confers re... multidrug resistance transporter 6 8   0
SES1 YDR023W Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoac... serine-tRNA ligase 6 56   0
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding ... replication factor C subunit 2|similar to human RFC 37 kDa subunit 5 39   0
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 5 15   0
VHS2 YIL135C Cytoplasmic protein of unknown function; identified as a high-copy suppressor of...   5 19   0
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome... Shuttling protein, ATP binding cassette protein 5 74   0
  YDL186W     5 5   0
LYS21 YDL131W Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha... YDL182W (LYS20) homolog|homocitrate synthase 5 17   0
SAS10 YDL153C Component of the small (ribosomal) subunit (SSU) processosome required for pre-1... U3 snoRNP protein 5 51   0
PRM10 YJL108C Pheromone-regulated protein, predicted to have 5 transmembrane segments   5 6   0
SSK1 YLR006C Cytoplasmic response regulator, part of a two-component signal transducer that m... two-component signal transducer that with Sln1p regulates osmosensing MAP kinase cascade(suppressor of sensor kinase) 5 18   0
  YNL284C-A     5 19   0
  YNR047W     5 25   0
MLF3 YNL074C Serine-rich protein of unknown function; overproduction suppresses the growth in...   5 16   0
RNT1 YMR239C RNAase III; cleaves a stem-loop structure at the 3- end of U2 snRNA to ensure fo... ribonuclease III 5 30   0
  YML045W-A     5 16   0
  YMR184W     5 19   0
YAP6 YDR259C Putative basic leucine zipper (bZIP) transcription factor; overexpression increa...   5 22   0
PHO23 YNL097C Probable component of the Rpd3 histone deacetylase complex, involved in transcri...   4 36   0.076
DCR2 YLR361C Putative phosphoesterase that functions as a dosage-dependent positive regulator...   4 2   0
TRM1 YDR120C tRNA methyltransferase, localizes to both the nucleus and mitochondrion to produ... N2,N2-dimethylguanosine-specific tRNA methyltransferase 4 16   0
  YKR105C     4 3   0
  YLR410W-A     4 7   0
  YBR197C     4 2   0
ARN2 YHL047C Transporter, member of the ARN family of transporters that specifically recogniz... triacetylfusarinine C transporter 4 1   0
SGE1 YPR198W Membrane-associated multidrug transporter, acts as an extrusion permease, member...   4 4   0
  YDR266C     4 15   0
SNP1 YIL061C Component of U1 snRNP required for mRNA splicing via spliceosome; may interact w... U1snRNP 70K protein homolog 4 92   0
HAC1 YFL031W bZIP transcription factor (ATF/CREB1 homolog) that regulates the unfolded protei... bZIP (basic-leucine zipper) protein 4 10   0.0038
  YMR046C     4 7   0
  YER093C-A     4 2   0
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding ... replication factor C subunit 5|similar to human RFC 38 kDa subunit 4 37   0.195
  YDR532C     4 12   0
HSP31 YDR533C Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S....   4 10   0
SIP5 YMR140W Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and...   4 30   0
  YBR285W     4 7   0
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multi... transcription factor 4 12   0

Service provided by the Mike Tyers Laboratory