Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for METHOXSALENZ-score WebGraph NB WebGraph
Targetspace hs 131 326
Targetspace hs pval0.210144927536230.037267080745342
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenot...   3 27   0.2392
HRB1 YNL004W Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus t... hypothetical RNA-binding protein 2 44   0.1895
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional ... chromatin remodeling Snf/Swi complex subunit 2 36   0
TAF1 YGR274C TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation,...   2 77   0.2186
MTW1 YAL034W-A Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p...   2 50   0
RTT107 YHR154W Protein that interacts with Mms22p and is implicated in Mms22-dependent DNA repa...   2 43   0
MMS1 YPR164W Protein likely involved in protection against replication-dependent DNA damage; ...   2 19   0.0108
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre... ribosomal protein S4A (YS6) (rp5) (S7A) 2 135   0.0014
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I), which phosphor... kinase subunit of RNA polymerase II carboxy-terminal domain kinase I 2 63   0
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9... ribosomal protein S9A (S13) (rp21) (YS11) 2 33   0
ITC1 YGL133W Component of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex, require...   2 28   0.1178
IML1 YJR138W Protein of unknown function, green fluorescent protein (GFP)-fusion protein loca...   2 34   0
CBF2 YGR140W Essential kinetochore protein, component of the CBF3 multisubunit complex that b... centromere binding factor CBF3 110 kDa subunit 2 39   0.2006
ABF2 YMR072W Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and ... HMG-1 homolog 2 45   0
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation, methylates ...   2 35 -0.8519 0
RFA1 YAR007C Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserv... RF-A|heterotrimeric RPA (RF-A) single-stranded DNA binding protein 69 kDa subunit 2 108   0
NHP10 YDL002C Protein related to mammalian high mobility group proteins; likely component of t... HMG1-box containing protein 2 51   0.1557
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member involved in genome ... high mobility group (HMG) family 2 99   0.2435
HAT2 YEL056W Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high ... histone acetyltransferase subunit 2 35   0
RGA2 YDR379W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... Rho-GTPase Activating Protein 2 25   0.0285
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and ... ribosomal protein S8A (S14A) (rp19) (YS9) 2 142   0.0472
RAD51 YER095W Strand exchange protein, forms a helical filament with DNA that searches for hom... Rad51p colocalizes to ~ 65 spots with Dmc1p prior to synapsis (independently of ZIP1 and DMC1), and interacts with Rad52p and Rad55p; human Rad51p homolog interacts with Brca2 protein which has been implicated in causing breast cancer|RecA homolog 2 56   0
RFA3 YJL173C Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserv... replication factor-A subunit 3 2 37   0
RAD52 YML032C Protein that stimulates strand exchange by facilitating Rad51p binding to single...   2 33 -5.2308 0
RFA2 YNL312W Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserv... 29% identical to the human p34 subunit of RF-A|replication factor RF-A subunit 2 2 37   0.1092
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis, forms a complex wit... human GTBP protein homolog 2 30   0
DNM1 YLL001W Dynamin-related GTPase required for mitochondrial fission and the maintenance of... similar to dynamin GTPase 2 20 -5.1254 0.2663
CTF8 YHR191C Subunit of a complex with Ctf18p that shares some subunits with Replication Fact...   2 11   0
HEX3 YDL013W Ring finger protein involved in the DNA damage response with possible recombinat...   2 57   0
RIM1 YCR028C-A Single-stranded DNA-binding protein essential for mitochondrial genome maintenan... DNA binding protein 2 31   0
RAD59 YDL059C Protein involved in the repair of double-strand breaks in DNA during vegetative ... the RAD59 gene product has homology to the Rad52 protein 2 34   0.2262
CTF18 YMR078C Subunit of a complex with Ctf8p that shares some subunits with Replication Facto...   2 24 -1.1478 0
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit; identical to Rps11Bp and... ribosomal protein S11A (S18A) (rp41A) (YS12) 2 88   0
ISW2 YOR304W Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodelin... ATPase component of a two subunit chromatin remodeling complex 2 40   0.2792
CPA1 YOR303W Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the s... arginine specific|carbamoyl phosphate synthetase 1 10   0
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit; nearly identical to Rps1... ribosomal protein S10A 1 13   0
HTB2 YBL002W One of two nearly identical (see HTB1) histone H2B subtypes required for chromat... histone H2B (HTB1 and HTB2 code for nearly identical proteins) 1 113   0
HIR1 YBL008W Non-essential transcriptional corepressor involved in the cell cycle-regulated t... contains nuclear targeting signal|repressor protein (putative)|similar to Tup1p and mammalian retinal transducin 1 19   0
CDC46 YLR274W Component of the hexameric MCM complex, which is important for priming origins o...   1 55   0.0293
MMS22 YLR320W Protein involved in resistance to ionizing radiation; acts with Mms1p in a repai...   1 29 -5.4467 0

Service provided by the Mike Tyers Laboratory