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SONAR Targetspace for DACTINOMYCINZ-score WebGraph NB WebGraph
Targetspace hs 273 212
Targetspace hs pval0.0614406779661020.39166666666667
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:30
Sym Orf Description Function No All Z_score hyperg
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   17 89   0.001
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing, interacts with Si...   13 51   NAN
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   12 94   NAN
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   12 79   0.0045
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor, may have a...   10 75   0
RAV2 YDR202C Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 dom...   10 103   0.0724
MRL1 YPR079W Membrane protein with similarity to mammalian mannose-6-phosphate receptors, pos...   10 55   0.0514
MUD1 YBR119W U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing U1 snRNP A protein 9 109   0
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 9 72   0
DBR1 YKL149C RNA lariat debranching enzyme, involved in intron turnover; required for efficie... RNA lariat debranching enzyme 9 56   0
STV1 YMR054W Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv... 110 kDa subunit; not in vacuole membrane|vacuolar H-ATPase 9 71   0
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 9 98   0
VPS13 YLL040C Protein of unknown function; heterooligomeric or homooligomeric complex; periphe...   9 137   0.0001
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   9 96   NAN
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   9 109   0.0256
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in pr... pol II transcribed genes regulator 8 80   0
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in tr... v-SNARE 8 62   0.1409
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   8 48   0
TVP15 YDR100W Integral membrane protein localized to late Golgi vesicles along with the v-SNAR... integral membrane protein 8 85   NAN
VMA7 YGR020C Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPa... vacuolar ATPase V1 domain subunit F (14 kDa) 8 51   0.1244
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   7 100   0.0011
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 7 37   0
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor, contains... polyadenylation factor subunit 7 35   0
  YOR112W     7 34   0.0714
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3, which is involved...   7 97   0
PIK1 YNL267W Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosp... phosphatidylinositol 4-kinase 7 121   0
  YIL039W     7 115   0
KNS1 YLL019C Nonessential putative protein kinase of unknown cellular role; member of the LAM... protein kinase homolog 7 54   0
DCR2 YLR361C Putative phosphoesterase that functions as a dosage-dependent positive regulator...   7 77   0
UTH1 YKR042W Mitochondrial outer membrane and cell wall localized SUN family member required ...   7 103   0

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