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SONAR Targetspace for CLOMIPRAMINE HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 249 325
Targetspace hs pval0.255639097744360.26515151515152
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
TRP2 YER090W Anthranilate synthase, catalyzes the initial step of tryptophan biosynthesis, fo... anthranilate synthase component I 6 76   0
LEM3 YNL323W Membrane protein of the plasma membrane and ER, involved in translocation of pho... membrane glycoprotein 6 113   0.0012
HMG2 YLR450W One of two isozymes of HMG-CoA reductase that convert HMG-CoA to mevalonate, a r... 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase isozyme 5 53   0
TGL3 YMR313C Triacylglycerol lipase of the lipid particle, responsible for all the TAG lipase... triacylglycerol lipase 5 31   0
DLD2 YDL178W D-lactate dehydrogenase, located in the mitochondrial matrix   5 12   0
TIM13 YGR181W Mitochondrial intermembrane space protein, forms a complex with TIm8p that medat...   4 108   0
EDS1 YBR033W Non-essential protein of unknown function   4 65   0
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p 4 96   0.0151
TDP1 YBR223C Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3--phosphotyrosyl bonds to generate ...   4 45   0.1119
OYE2 YHR179W Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), ho... NAPDH dehydrogenase (old yellow enzyme), isoform 2 4 72   0
YPT10 YBR264C GTP binding protein that contains the PEST signal sequence specific for proteoly...   4 37   0
TOP2 YNL088W Essential type II topoisomerase, relieves torsional strain in DNA by cleaving an... topoisomerase II 4 65   0.0104
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese tr... inorganic phosphate transporter 4 72   0
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3... histone acetyltransferase complex component 4 49   0.0009
RPG1 YBR079C Subunit of the core complex of translation initiation factor 3(eIF3), essential ... translation initiation factor eIF3 subunit 4 105   0
DOA4 YDR069C Ubiquitin hydrolase, required for recycling ubiquitin from proteasome-bound ubiq... ubiquitin isopeptidase 4 97 -3.2340 0.0104
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in phospholipid metabolism; hydroly... phospholipase B (lysophospholipase) 4 52   0
  YHR009C     3 22   0
SCS3 YGL126W Protein required for inositol prototrophy, appears to be involved in the synthes...   3 99   0
YBP1 YBR216C Protein required for oxidation of specific cysteine residues of the transcriptio... redox regulator 3 17   0
CAX4 YGR036C Dolichyl pyrophosphate (Dol-P-P) phosphatase with a luminally oriented active si... contains 3 short stretches of amino acids that are characteristic for a wide variety of phosphatases, including lipid phosphatases and a protein phosphatase 3 30   0
LEU1 YGL009C Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis... isopropylmalate isomerase 3 32   0
RPC31 YNL151C RNA polymerase III subunit C31; contains HMG-like C-terminal domain HMG1-like protein|RNA polymerase III (C) 31 kDa subunit 3 61   0.0031
ZRC1 YMR243C Vacuolar membrane zinc transporter, transports zinc from the cytosol into the va...   3 65   0
CYS3 YAL012W Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the tr... cystathionine gamma-lyase 3 100   0
EXO70 YJL085W Essential 70kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec1... exocyst complex component 3 85   0
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps2... ribosomal protein S29B (S36B) (YS29) 3 43   0.0193
TPD3 YAL016W Regulatory subunit A of the heterotrimeric protein phosphatase 2A, which also co... protein phosphatase 2A regulatory subunit A 3 59   0
PRE10 YOR362C 20S proteasome alpha-type subunit proteasome component YC1 (protease yscE subunit 1) 3 80   0
PCK1 YKR097W Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes earl... phosphoenolpyruvate carboxylkinase 3 68   0
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mit... Phb2p homolog|mitochondrial protein 3 131   0.0012
FYV10 YIL097W Protein of unknown function, required for survival upon exposure to K1 killer to...   3 125   0
TIR4 YOR009W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins... cell wall mannoprotein 3 34   0
COX7 YMR256C Subunit VII of cytochrome c oxidase, which is the terminal member of the mitocho... cytochrome c oxidase subunit VII 3 125   0
MMS21 YEL019C SUMO ligase involved in chromosomal organization and DNA repair; essential subun...   3 35   0.0636
  YMR247C     3 21   0.1737
APL4 YPR029C Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; ... clathrin associated protein complex large subunit|gamma-adaptin 3 104   0
SSH4 YKL124W Protein whose overexpression confers resistance to the growth inhibitor leflunom...   3 15   0
RSM22 YKL155C Mitochondrial ribosomal protein of the small subunit mitochondrial ribosome small subunit component 3 52   0.0007

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