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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
QRI8 YMR022W Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation ... ubiquitin-conjugating enzyme 8 69   0.1506
SEC12 YNR026C Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein... guanine nucleotide exchange factor for Sar1p 8 27   0
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding and autopha... vesicle coat component 8 14   0
SEC13 YLR208W Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (S... nuclear pore complex subunit|protein involved in release of transport vesicles from the ER 8 25   0
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 ... compass (complex proteins associated with Set1p) component 6 69   0.0942
SIN4 YNL236W Subunit of the Mediator complex; interacts with the RNA polymerase II holoenzyme... RNA polymerase II holoenzyme/mediator subunit 5 59   0.0995
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that act...   5 142   0
SEC23 YPR181C GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex ... GTPase activating protein (GAP) 5 30   0.0001
SAR1 YPL218W GTPase, GTP-binding protein of the ARF family, component of COPII coat of vesicl... ARF family|GTP-binding protein 4 14   0
LRS4 YDR439W Protein involved in rDNA silencing; positively charged coiled-coil protein with ...   4 106   0.1637
ERD2 YBL040C Integral membrane protein that binds to the HDEL motif in proteins destined for ... HDEL receptor 4 8   0.0067
SEC17 YBL050W Peripheral membrane protein required for vesicular transport between ER and Golg...   4 11   0
SLX8 YER116C Protein containing a RING finger domain that forms a complex with Hex3p; mutant ...   4 121   0
KAR2 YJL034W ATPase involved in protein import into the ER, also acts as a chaperone to media... HSP70 family|mammalian BiP (GRP78 or HSPA5) homolog 4 20   0
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   4 61   0.0153
EAP1 YKL204W eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, al...   4 25   0.0347
PIF1 YML061C DNA helicase involved in telomere formation and elongation; acts as a catalytic ... 5--3- DNA helicase 4 104   0.1797
RTT107 YHR154W Protein that interacts with Mms22p and is implicated in Mms22-dependent DNA repa...   4 94   0
HAC1 YFL031W bZIP transcription factor (ATF/CREB1 homolog) that regulates the unfolded protei... bZIP (basic-leucine zipper) protein 4 50   0.0038
SEC31 YDL195W Essential phosphoprotein component (p150) of the COPII coat of secretory pathway... COPII coat of secretory pathway vesicles component (p150) 4 9   0
ARV1 YLR242C Protein required for normal intracellular sterol distribution and for sphingolip... Protein involved in sterol distribution 4 20   0.151
  YBR138C     4 1   0
UFE1 YOR075W t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane... t-SNARE (ER) 4 18   0.0007
  YKL206C     4 3   0
HRD1 YOL013C Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradati...   4 61   0.0794
DER1 YBR201W Endoplasmic reticulum membrane protein, required for ER-associated protein degra...   4 20   0.1431
HEM1 YDR232W 5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pa... 5-aminolevulinate synthase 4 10   0
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec1... exocyst complex component 4 43   0.1797
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; ... vesicle coat component 4 11   0.1347
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide ... Hsp70 family 4 80   0.0648
COS8 YHL048W Nuclear membrane protein, member of the DUP380 subfamily of conserved, often sub...   4 4   0
ERJ5 YFR041C Endoplasmic reticulum protein that may function as a cochaperone, as suggested b...   4 8   0
MGM101 YJR144W Protein involved in mitochondrial genome maintenance; component of the mitochond... mitochondrial nucleoid protein 3 14   0.0675
END3 YNL084C EH domain-containing protein involved in endocytosis, actin cytoskeletal organiz...   3 51   0.1963
LSM7 YNL147W Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either L... snRNP protein 3 52   0.0015
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-I) with Cac2p and M... chromatin assembly factor-I (CAF-I) p90 subunit 3 74   0.0003
PDI1 YCL043C Protein disulfide isomerase, multifunctional protein resident in the endoplasmic... protein disulfide isomerase 3 123   0

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