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SONAR Targetspace for METHOXSALENZ-score WebGraph NB WebGraph
Targetspace hs 131 326
Targetspace hs pval0.210144927536230.037267080745342
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
TSA1 YML028W Ubiquitous housekeeping thioredoxin peroxidase, reduces reactive oxygen, nitroge... thioredoxin peroxidase 5 147   0.1941
PIF1 YML061C DNA helicase involved in telomere formation and elongation; acts as a catalytic ... 5--3- DNA helicase 5 104   0.1887
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition; structurally an... DNA helicase 4 93   0.0015
MUS81 YDR386W Helix-hairpin-helix protein, involved in DNA repair and replication fork stabili...   4 72   0
ORC6 YHR118C Subunit of the origin recognition complex, which directs DNA replication by bind... ORC 50 kDa subunit 3 34   0.0301
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length... DNA binding protein 3 71   0.0371
RFA1 YAR007C Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserv... RF-A|heterotrimeric RPA (RF-A) single-stranded DNA binding protein 69 kDa subunit 3 43   0
CAC2 YML102W Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assemble... chromatin assembly factor-I (CAF-I) p60 subunit 3 45   0.0064
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric...   3 71   0.0002
SMC1 YFL008W Subunit of the multiprotein cohesin complex, essential protein involved in chrom... SMC chromosomal ATPase family member 3 17   0.0166
RAD24 YER173W Checkpoint protein, involved in the activation of the DNA damage and meiotic pac... cell cycle exonuclease (putative) 3 118   0.0001
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenot...   2 59   0.2236
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor required for oxidative stress t... jun-like transcription factor 2 39   0.2706
CKB2 YOR039W Beta- regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles... protein kinase CK2, beta- subunit 2 30   0.2626
SKN7 YHR206W Nuclear response regulator and transcription factor, part of a branched two-comp...   2 45   0.2793
RAD59 YDL059C Protein involved in the repair of double-strand breaks in DNA during vegetative ... the RAD59 gene product has homology to the Rad52 protein 2 53   0.2262
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodim... ATP dependent DNA ligase 2 15   0.0596
BUD16 YEL029C Protein involved in bud-site selection and telomere maintenance; diploid mutants...   2 10   0.1202
SLX8 YER116C Protein containing a RING finger domain that forms a complex with Hex3p; mutant ...   2 121   0
NTG1 YAL015C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision... DNA glycosylase 2 23   0.0755
UMP1 YBR173C Short-lived chaperone required for correct maturation of the 20S proteasome; deg... 20S proteasome maturation factor 2 24   0.0137
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis, postmeiotic segrega... mutL homolog 2 27   0.0024
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision... endonuclease III DNA base excision repair N-glycosylase 2 23   0.0003
MSH2 YOL090W Protein that forms heterodimers, with Msh3p and Msh6p, that bind to DNA mismatch... mutS homolog 2 53   0.0174
TOP3 YLR234W DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p ... DNA topoisomerase III 2 73   0.031
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation as the recruit... Telomere elongation protein 2 30   0.1321
SIZ1 YDR409W SUMO ligase that promotes the attachment of sumo (Smt3p; small ubiquitin-related... chromatin protein; SUMO1/Smt3 ligase 2 40   0.0755
WSS1 YHR134W Sumoylated protein of unknown function, identified based on genetic interactions...   2 28   0.0061
APN1 YKL114C Major apurinic/apyrimidinic endonuclease, 3--repair diesterase involved in repai... major apurinic/apyrimidinic endonuclease/3--repair diesterase 2 62   0.1703
TRM2 YKR056W tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs... tRNA methyltransferase 2 6   0.1154
SFH1 YLR321C Subunit of the RSC chromatin remodeling complex required for kinetochore functio... Snf5p homolog|chromatin remodeling complex member, RSC 2 6   0.1006
RIM11 YMR139W Protein kinase required for signal transduction during entry into meiosis; promo...   2 10   0.0844
RAD5 YLR032W Single-stranded DNA-dependent ATPase, involved in postreplication repair; contai... ATPase (putative)|DNA helicase (putative) 2 133   0
HST3 YOR025W Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved alo...   2 74   0.2739
FZO1 YBR179C Mitochondrial integral membrane protein involved in mitochondrial fusion and mai... Drosophila melanogaster fuzzy onions gene homolog|integral protein of the mitochondrial outer membrane; can be isolated as part of a high molecular weight complex 2 16   0.0549
HST4 YDR191W Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved alo...   2 37   0.0007
MCM2 YBL023C Protein involved in DNA replication; component of the Mcm2-7 hexameric complex t...   2 23   0

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