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SONAR Targetspace for DACTINOMYCINZ-score WebGraph NB WebGraph
Targetspace hs 273 212
Targetspace hs pval0.0614406779661020.39166666666667
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:35
Sym Orf Description Function No All Z_score hyperg
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 23 67 -0.1356 0
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic; regulates potassiu... ADP-ribosylation factor-like protein 1 22 141   0
TLG2 YOL018C Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fus... tSNARE that affects a late Golgi compartment 21 128   0
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   21 48   0.0399
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   19 42 -36.4693 0
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   19 32   0
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   19 41   0
BRE5 YNR051C Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that core...   18 121   NAN
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   18 21   0
PAP2 YOL115W Catalytic subunit of TRAMP (Trf4/Pap2p-Mtr4p-Air1p/2p), a nuclear poly (A) polym... DNA polymerase sigma|poly(A) polymerase 17 119   0
DCR2 YLR361C Putative phosphoesterase that functions as a dosage-dependent positive regulator...   17 19   0.0105
SKY1 YMR216C SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabo...   16 97   0.0889
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   16 30   0
GSG1 YDR108W Subunit of TRAPP (transport protein particle), a multi-subunit complex involved ...   16 97   0
ERV14 YGL054C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... 14 kDa protein found on ER-derived vesicles 16 76   NAN
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   15 41   NAN
IMH1 YLR309C Protein involved in vesicular transport, mediates transport between an endosomal...   15 4   0.097
BRE2 YLR015W Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 ... compass (complex proteins associated with Set1p) component 15 61   0
VPS74 YDR372C Non-essential protein of unknown function involved in vacuolar protein sorting; ...   15 47   0
MAK3 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for... N-acetyltransferase 15 20   0
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... function unknown 14 110   0.0257
  YIL039W     14 65   NAN
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   14 12   0
GET3 YDL100C ATPase, subunit of the GET complex; required for the retrieval of HDEL proteins ...   14 110   0.1196
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing, interacts with Si...   13 10   NAN
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleot...   13 66 -19.4150 0
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   13 57   NAN
PIK1 YNL267W Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosp... phosphatidylinositol 4-kinase 13 108   0
INP53 YOR109W Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein w... inositol polyphosphate 5-phosphatase 13 77   0
SWA2 YDR320C Auxilin-like protein involved in vesicular transport; clathrin-binding protein r... auxilin-like protein 12 24   0
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   12 73   0.1292
MID1 YNL291C N-glycosylated integral membrane protein of the ER membrane and plasma membrane,... N-glycosylated integral plasma membrane protein 12 28   0.0005
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxy...   12 31   0
FUN30 YAL019W Protein whose overexpression affects chromosome stability, potential Cdc28p subs...   12 27   0.039
VAM10 YOR068C Protein involved in vacuole morphogenesis; acts at an early step of homotypic va... Required for normal tethering of vacuoles prior to fusion. 12 18   0

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