Compound Information | SONAR Target prediction | Name: | HOMIDIUM BROMIDE | Unique Identifier: | SPE01503806 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | | Molecular Weight: | 374.149 g/mol | X log p: | 22.536 (online calculus) | Lipinksi Failures | 1 | TPSA | 3.01 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 2 | Rotatable Bond Count: | 2 | Canonical Smiles: | [BrH-].CC[n+]1c2cc(N)ccc2c2ccc(N)cc2c1c1ccccc1 | Source: | synthetic | Reference: | J Mol Biol 13: 269 (1965); 27: 87 (1967) | Therapeutics: | antiprotozoal, intercalcate with DNA |
Species: |
4932 |
Condition: |
MMS22 |
Replicates: |
2 |
Raw OD Value: r im |
0.4998±0.0124451 |
Normalized OD Score: sc h |
0.8721±0.0144554 |
Z-Score: |
-4.1768±0.223626 |
p-Value: |
0.0000365546 |
Z-Factor: |
-0.397208 |
Fitness Defect: |
10.2167 |
Bioactivity Statement: |
Active |
Experimental Conditions | | Library: | SPECMTS3 | Plate Number and Position: | 5|D6 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 26.80 Celcius | Date: | 2008-06-13 YYYY-MM-DD | Plate CH Control (+): | 0.040625±0.00065 | Plate DMSO Control (-): | 0.56075±0.02361 | Plate Z-Factor: | 0.8816 |
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DBLink | Rows returned: 6 | |
3624 |
5-ethyl-6-phenyl-phenanthridine-3,8-diamine |
11765 |
5-ethyl-6-phenyl-phenanthridine-3,8-diamine chloride |
14710 |
5-ethyl-6-phenyl-phenanthridine-3,8-diamine bromide |
152350 |
5-ethyl-6-naphthalen-2-yl-phenanthridine-3,8-diamine |
174724 |
5-ethyl-6-phenyl-phenanthridine-3,8-diamine |
3896235 |
(8-amino-5-ethyl-6-phenyl-phenanthridin-3-yl)azanium |
internal high similarity DBLink | Rows returned: 0 | |
nonactive | Cluster 6881 | Additional Members: 3 | Rows returned: 1 | |
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