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Compound InformationSONAR Target prediction
Name:

p-FLUOROPHENYLALANINE

Unique Identifier:SPE01502114
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:173.1 g/mol
X log p:7.173  (online calculus)
Lipinksi Failures1
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:3
Canonical Smiles:NC(Cc1ccc(F)cc1)C(O)=O
Source:synthetic
Reference:J Biol Chem 269: 24637 ((1994); Biochemistry 35: 6969 (1996); Eur J Cell Biol 23:
312 (1981)
Therapeutics:amino acid antagonist, protein synthesis inhibitor

Found: 205 nonactive as graph: single | with analogs [1] << Back 41 42 43 44 45 46 47 48 49 50  Next >> [205]
Species: 4932
Condition: IRE1
Replicates: 2
Raw OD Value: r im 0.7366±0.00565685
Normalized OD Score: sc h 1.0262±0.0131423
Z-Score: 1.8489±0.763741
p-Value: 0.103744
Z-Factor: -7.16038
Fitness Defect: 2.2658
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:10|D4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.00 Celcius
Date:2007-11-23 YYYY-MM-DD
Plate CH Control (+):0.0403±0.00049
Plate DMSO Control (-):0.70395±0.12541
Plate Z-Factor:0.4070
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DBLink | Rows returned: 71 2 Next >> 
4654 2-amino-3-(4-fluorophenyl)propanoic acid
450592 2-amino-3-(4-fluorophenyl)propanoic acid
450593 (2S)-2-amino-3-(4-fluorophenyl)-2-methyl-propanoic acid
716312 (2S)-2-amino-3-(4-fluorophenyl)propanoic acid
716314 (2R)-2-amino-3-(4-fluorophenyl)propanoic acid
6926425 (2S)-2-azaniumyl-3-(4-fluorophenyl)propanoate

internal high similarity DBLink | Rows returned: 1
LOPAC 00912 1.0000

active | Cluster 1385 | Additional Members: 11 | Rows returned: 0
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