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Compound InformationSONAR Target prediction
Name:

p-FLUOROPHENYLALANINE

Unique Identifier:SPE01502114
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:173.1 g/mol
X log p:7.173  (online calculus)
Lipinksi Failures1
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:3
Canonical Smiles:NC(Cc1ccc(F)cc1)C(O)=O
Source:synthetic
Reference:J Biol Chem 269: 24637 ((1994); Biochemistry 35: 6969 (1996); Eur J Cell Biol 23:
312 (1981)
Therapeutics:amino acid antagonist, protein synthesis inhibitor

Found: 205 nonactive as graph: single | with analogs 1 2 3 4 5 6 7 8 9 10  Next >> [205]
Species: 4932
Condition: APC9
Replicates: 2
Raw OD Value: r im 0.7161±0.000707107
Normalized OD Score: sc h 1.0267±0.00114726
Z-Score: 1.4513±0.0404447
p-Value: 0.146866
Z-Factor: -7.82938
Fitness Defect: 1.9182
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:10|D4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:23.10 Celcius
Date:2007-11-22 YYYY-MM-DD
Plate CH Control (+):0.04245±0.00129
Plate DMSO Control (-):0.685975±0.12244
Plate Z-Factor:0.4058
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DBLink | Rows returned: 71 2 Next >> 
4654 2-amino-3-(4-fluorophenyl)propanoic acid
450592 2-amino-3-(4-fluorophenyl)propanoic acid
450593 (2S)-2-amino-3-(4-fluorophenyl)-2-methyl-propanoic acid
716312 (2S)-2-amino-3-(4-fluorophenyl)propanoic acid
716314 (2R)-2-amino-3-(4-fluorophenyl)propanoic acid
6926425 (2S)-2-azaniumyl-3-(4-fluorophenyl)propanoate

internal high similarity DBLink | Rows returned: 1
LOPAC 00912 1.0000

nonactive | Cluster 1385 | Additional Members: 11 | Rows returned: 6
LOPAC 01033 0.444444444444444
SPE01500382 0.444444444444444
SPE01502162 0.384615384615385
LOPAC 00493 0.384615384615385
LOPAC 00912 0
LAT003F10 0

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