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Compound InformationSONAR Target prediction
Name:

LANOSTEROL

Unique Identifier:SPE00240470
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C30H50O
Molecular Weight:376.32 g/mol
X log p:2.412  (online calculus)
Lipinksi Failures0
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:4
Canonical Smiles:CC(CCC=C(C)C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC4(C)C=3CCC12C
Source:ex wool fat of sheep
Generic_name:LANOSTEROL
Chemical_iupac_name:LANOSTEROL
Drug_type:Experimental
Kegg_compound_id:C01724
Drugbank_id:EXPT02002
Logp:7.63
Cas_registry_number:79-63-0
Drug_category:Lanosterol Synthase inhibitor
Organisms_affected:-1

Found: 3 active | as graph: single | with analogs << Back 1 2 3 Next >> 
Species: 4932
Condition: MRT4
Replicates: 2
Raw OD Value: r im 0.4335±0.0609526
Normalized OD Score: sc h 0.8222±0.0123146
Z-Score: -5.9348±1.26836
p-Value: 0.000000235352
Z-Factor: -3.03155
Fitness Defect: 15.2622
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:4|G6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.90 Celcius
Date:2007-08-30 YYYY-MM-DD
Plate CH Control (+):0.0395±0.00061
Plate DMSO Control (-):0.5116499999999999±0.09917
Plate Z-Factor:0.3262
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DBLink | Rows returned: 277[1] << Back 21 22 23 24 25 26 27 28 29 30  Next >> [47]
3083379 n/a
3084367 (3S,4aS,6aS,6bS,8aR,11R,12S,12aR,14bS)-4,4,6a,6b,8a,11,12,14b-octamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,1
3,14-tetradecahydro-1H-picen-3-ol
3312783 4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,13,14-tetradecahydropicen-3-ol
3375145 10,13-dimethyl-17-(6-methyl-5-methylidene-heptan-2-yl)-2,3,4,5,6,7,11,12,14,15,16,17-dodecahydro-1H-cycl
openta[a]phenanthren-3-ol
3710743 17-hex-5-en-2-yl-4,4,10,14-tetramethyl-1,2,3,5,6,7,11,12,13,15,16,17-dodecahydrocyclopenta[a]phenanthren
-3-ol
4227079 1,1,4a-trimethyl-2,3,4,5,8,8a-hexahydronaphthalen-2-ol

internal high similarity DBLink | Rows returned: 112 Next >> 
SPE01504073 0.9167
SPE01504051 0.9189
SPE01500847 0.9189
SPE00107022 0.9189
SPE00300055 0.9444
NRB 03722 0.9706

active | Cluster 1278 | Additional Members: 6 | Rows returned: 2
SPE00100583 0.253012048192771
SPE00201697 0

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