Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

(±)-Thalidomide

Unique Identifier:LOPAC 01279
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C13H10N2O4
Molecular Weight:248.15 g/mol
X log p:6.737  (online calculus)
Lipinksi Failures1
TPSA71.52
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:1
Canonical Smiles:O=C1CCC(n2c(=O)c3ccccc3c2=O)C(=O)N1
Class:Cytoskeleton and ECM
Action:Inhibitor
Selectivity:TNFalpha

Found: 24 nonactive as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [24]
Species: 4932
Condition: PAC10
Replicates: 2
Raw OD Value: r im 0.7446±0.00650538
Normalized OD Score: sc h 1.0118±0.0000156778
Z-Score: 0.5369±0.0061001
p-Value: 0.59132
Z-Factor: -4.79523
Fitness Defect: 0.5254
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:16|C5
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.70 Celcius
Date:2005-04-15 YYYY-MM-DD
Plate CH Control (+):0.046925±0.00161
Plate DMSO Control (-):0.7003750000000001±0.04238
Plate Z-Factor:0.9455
png
ps
pdf

DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 7702 | Additional Members: 4 | Rows returned: 2
Prest463 0
SPE01503607 0

Service provided by the Mike Tyers Laboratory