Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

Colchicine

Unique Identifier:LOPAC 00810
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C22H25NO6
Molecular Weight:374.239 g/mol
X log p:9.286  (online calculus)
Lipinksi Failures1
TPSA71.06
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:7
Rotatable Bond Count:6
Canonical Smiles:COC1=CC=C2C(=CC1=O)C(CCc1cc(OC)c(OC)c(OC)c12)NC(C)=O
Class:Cytoskeleton and ECM
Action:Inhibitor
Selectivity:Tubulin

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: CLN3
Replicates: 2
Raw OD Value: r im 0.6602±0.0187383
Normalized OD Score: sc h 0.9496±0.0285844
Z-Score: -1.6717±0.708308
p-Value: 0.135731
Z-Factor: -11.2499
Fitness Defect: 1.9971
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:4|G11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.80 Celcius
Date:2005-05-08 YYYY-MM-DD
Plate CH Control (+):0.04785±0.00081
Plate DMSO Control (-):0.6973±0.04791
Plate Z-Factor:0.6869
png
ps
pdf

DBLink | Rows returned: 71 2 Next >> 
2833
6167
23758
53278
450692
537229

internal high similarity DBLink | Rows returned: 3
SPE01800067 0.9440
BTB 12749 1.0000
SPE01500205 1.0000

active | Cluster 2172 | Additional Members: 11 | Rows returned: 3
Prest353 0.493506493506494
Prest875 0.386363636363636
SPE01800067 0.217391304347826

Service provided by the Mike Tyers Laboratory