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Compound InformationSONAR Target prediction
Name:

Colchicine

Unique Identifier:LAT004G11
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C22H25NO6
Molecular Weight:374.239 g/mol
X log p:9.286  (online calculus)
Lipinksi Failures1
TPSA71.06
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:7
Rotatable Bond Count:6
Canonical Smiles:COC1=CC=C2C(=CC1=O)C(CCc1cc(OC)c(OC)c(OC)c12)NC(C)=O

Found: 5 nonactive as graph: single | with analogs 1 2 3 4 5 Next >> 
Species: 4932
Condition: pdr18h
Replicates: 2
Raw OD Value: r im 0.6242±0.00247487
Normalized OD Score: sc h 0.9916±0.0118851
Z-Score: -0.1099±0.347505
p-Value: 0.807042
Z-Factor: -8.63696
Fitness Defect: 0.2144
Bioactivity Statement: Nonactive
Experimental Conditions
Library:LATCA
Plate Number and Position:4|G11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.20 Celcius
Date:2007-03-08 YYYY-MM-DD
Plate CH Control (+):0.040825±0.00277
Plate DMSO Control (-):0.640525±0.21231
Plate Z-Factor:-0.0729
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DBLink | Rows returned: 161 2 3 Next >> 
2833
6167
23758
53278
450692
537229

internal high similarity DBLink | Rows returned: 5
BIOMOL 86 1.0000
BTB 12749 1.0000
LOPAC 00810 1.0000
Prest695 1.0000
SPE01500205 1.0000

active | Cluster 2172 | Additional Members: 11 | Rows returned: 3
Prest353 0.493506493506494
Prest875 0.386363636363636
SPE01800067 0.217391304347826

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