ChemGrid

CHEMGRID MOLECULE CARD

CLONAZEPAM

CLONAZEPAM in ChemGrid: 13 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01505958

Explore activity & SONAR
Chemical structure of CLONAZEPAM
Stored molecular structure
13Screened assays
0Significant assay responses
6Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE01505958
Molecular formula
C15ClH10N3O3
CAS registry number
1622-61-3
InChIKey
DGBIGWXXNGSACT-UHFFFAOYSA-N
Libraries
Spectrum_ED
Other recorded names
Clonazepam
Stored SMILES[O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3Cl)c2c1

Matched external records: PubChem 2802

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

13 measurements across 13 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
ADRA1A · Alpha-1A adrenergic receptorChEMBLNo stored yeast mapping
Cckar · Cholecystokinin receptorChEMBLNo stored yeast mapping
Cckar · Cholecystokinin receptor type AChEMBLNo stored yeast mapping
Gabra1 · Gamma-aminobutyric acid receptor subunit alpha-1ChEMBLNo stored yeast mapping
Gabrp · GABA-A receptor; anion channelChEMBLNo stored yeast mapping
TSPO · Translocator proteinChEMBLNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete CLONAZEPAM research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.