CHEMGRID MOLECULE CARD
TRICHLORFON
TRICHLORFON in ChemGrid: 13 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01505765
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01505765
- Molecular formula
- C4Cl3H8O4P
- CAS registry number
- 52-68-6
- InChIKey
- NFACJZMKEDPNKN-UHFFFAOYSA-N
- Libraries
- Spectrum_ED
- Other recorded names
- Trichlorfon
Stored SMILES
COP(=O)(OC)C(O)C(Cl)(Cl)ClMatched external records: PubChem 5853
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
13 measurements across 13 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ACHE · Acetylcholinesterase | ChEMBL | No stored yeast mapping |
| AR · Androgen receptor | ChEMBL | No stored yeast mapping |
| ESR1 · Estrogen receptor | ChEMBL | No stored yeast mapping |
| GMNN · Geminin | ChEMBL | No stored yeast mapping |
| LMNA · Prelamin-A/C | ChEMBL | No stored yeast mapping |
| MBNL1 · Muscleblind-like protein 1 | ChEMBL | No stored yeast mapping |
| NFE2L2 · Nuclear factor erythroid 2-related factor 2 | ChEMBL | No stored yeast mapping |
| NR1H4 · Bile acid receptor | ChEMBL | No stored yeast mapping |
| PPARD · Peroxisome proliferator-activated receptor delta | ChEMBL | No stored yeast mapping |
| RXRA · Retinoic acid receptor RXR-alpha | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete TRICHLORFON research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.