ChemGrid

CHEMGRID MOLECULE CARD

RONNEL

RONNEL in ChemGrid: 13 screened assays, 13 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01505668

Explore activity & SONAR
Chemical structure of RONNEL
Stored molecular structure
13Screened assays
13Significant assay responses
3Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE01505668
Molecular formula
C8Cl3H8O3PS
CAS registry number
299-84-3
InChIKey
JHJOOSLFWRRSGU-UHFFFAOYSA-N
Libraries
Spectrum_ED
Other recorded names
Fenchlorphos
Stored SMILESCOP(=S)(OC)Oc1cc(Cl)c(Cl)cc1Cl

Matched external records: PubChem 9298

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

13 measurements across 13 distinct library–species–strain assays; 13 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Up to 12 strongest recorded single-strain responses by absolute Z-score
StrainLibrarySpecies identifierZ-score
BY4741-3rdSpectrum_ED4932-53.24
BY4743Spectrum_ED4932-44.07
BY4741-2ndSpectrum_ED4932-36.32
pdr_yCG196Spectrum_ED4932-28.93
BCK1Spectrum_ED4932-28.65
NPR1Spectrum_ED4932-28.08
TOR1Spectrum_ED4932-26.69
MKK1Spectrum_ED4932-24.25
SLT2Spectrum_ED4932-24.03
HOG1Spectrum_ED4932-23.04
IRE1Spectrum_ED4932-22.97
BY4741Spectrum_ED4932-19.83

Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
Luciferin 4-monooxygenaseChEMBLNo stored yeast mapping
AR · Androgen receptorChEMBLNo stored yeast mapping
NFE2L2 · Nuclear factor erythroid 2-related factor 2ChEMBLNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete RONNEL research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.