CHEMGRID MOLECULE CARD
BIPERIDEN
BIPERIDEN in ChemGrid: 104 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01505514
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01505514
- Molecular formula
- C21H29NO
- CAS registry number
- 514-65-8
- InChIKey
- YSXKPIUOCJLQIE-UHFFFAOYSA-N
- Libraries
- SPECMTS3, Spectrum_ED
- Other recorded names
- Biperiden
Stored SMILES
OC(CCN1CCCCC1)(C1CC2CC1C=C2)c1ccccc1Matched external records: PubChem 2381
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
104 measurements across 104 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Luciferin 4-monooxygenase | ChEMBL | No stored yeast mapping |
| ARSA · Arylsulfatase A | ChEMBL | No stored yeast mapping |
| CHRM1 · Muscarinic acetylcholine receptor M1 | ChEMBL | No stored yeast mapping |
| CHRM2 · Muscarinic acetylcholine receptor M2 | ChEMBL | No stored yeast mapping |
| CHRM3 · Muscarinic acetylcholine receptor M3 | ChEMBL | No stored yeast mapping |
| CHRM4 · Muscarinic acetylcholine receptor M4 | ChEMBL | No stored yeast mapping |
| FEN1 · Flap endonuclease 1 | ChEMBL | RAD27 YKL113C (ortholog_one2one) |
| KCNH2 · Voltage-gated inwardly rectifying potassium channel KCNH2 | ChEMBL | No stored yeast mapping |
| Ptgs1 · Prostaglandin G/H synthase 1 | ChEMBL | No stored yeast mapping |
| PTGS2 · Prostaglandin G/H synthase 2 | ChEMBL | No stored yeast mapping |
| Txnrd1 · Thioredoxin reductase 1, cytoplasmic | ChEMBL | TRR1 YDR353W (ortholog_many2many); TRR2 YHR106W (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete BIPERIDEN research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.