CHEMGRID MOLECULE CARD

METHYLDOPATE HYDROCHLORIDE

METHYLDOPATE HYDROCHLORIDE in ChemGrid: 104 screened assays, 1 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01505384

Explore activity & SONAR

Chemical structure of METHYLDOPATE HYDROCHLORIDE — Stored molecular structure

104Screened assays

1Significant assay responses

0Source-labelled target records

Identity and chemistry

ChemGrid identifier: SPE01505384
Molecular formula: C12ClH18NO4
CAS registry number: 2508-79-4
InChIKey: QSRVZCCJDKYRRF-UHFFFAOYSA-N
Libraries: SPECMTS3, Spectrum_ED
Other recorded names: Ethyl 2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoate;hydrochloride

Stored SMILES

Cl.CCOC(=O)C(C)(N)Cc1ccc(O)c(O)c1

Matched external records: PubChem 21585236

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

104 measurements across 104 distinct library–species–strain assays; 1 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Up to 12 strongest recorded single-strain responses by absolute Z-score
Strain	Library	Species identifier	Z-score
vam3	SPECMTS3	4932	-4.31

Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.

Recorded target evidence and yeast matches

No source-labelled target annotations are stored for this identifier in this snapshot. This does not mean the molecule has no biological targets.

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete METHYLDOPATE HYDROCHLORIDE research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.