ChemGrid

CHEMGRID MOLECULE CARD

TRIADIMEFON

TRIADIMEFON in ChemGrid: 104 screened assays, 103 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01505307

Explore activity & SONAR
Chemical structure of TRIADIMEFON
Stored molecular structure
104Screened assays
103Significant assay responses
4Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE01505307
Molecular formula
C14ClH16N3O2
CAS registry number
43121-43-3
InChIKey
WURBVZBTWMNKQT-UHFFFAOYSA-N
Libraries
SPECMTS3, Spectrum_ED
Other recorded names
Triadimefon
Stored SMILESCC(C)(C)C(=O)C(Oc1ccc(Cl)cc1)n1cncn1

Matched external records: PubChem 39385

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

104 measurements across 104 distinct library–species–strain assays; 103 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Up to 12 strongest recorded single-strain responses by absolute Z-score
StrainLibrarySpecies identifierZ-score
hsp104SPECMTS34932-51.63
BY4741SPECMTS34932-50.95
gyp1SPECMTS34932-49.78
snc1SPECMTS34932-49.20
BY4743Spectrum_ED4932-48.92
aat2SPECMTS34932-47.01
vba3SPECMTS34932-46.96
rbl2SPECMTS34932-46.89
sdh2SPECMTS34932-46.88
bck1SPECMTS34932-46.87
paf1SPECMTS34932-46.85
hsp82SPECMTS34932-46.48

Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
cyp51 · Cytochrome P450 14alpha-demethylaseChEMBLERG11 YHR007C (ortholog_one2one)
ESR1 · Estrogen receptorChEMBLNo stored yeast mapping
POLI · DNA polymerase iotaChEMBLNo stored yeast mapping
TARDBP · TAR DNA-binding protein 43ChEMBLPIN4 YBL051C (ortholog_many2many)

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete TRIADIMEFON research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.