ChemGrid

CHEMGRID MOLECULE CARD

OXFENDAZOLE

OXFENDAZOLE in ChemGrid: 104 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01505296

Explore activity & SONAR
Chemical structure of OXFENDAZOLE
Stored molecular structure
104Screened assays
0Significant assay responses
3Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE01505296
Molecular formula
C15H13N3O3S
CAS registry number
53716-50-0
InChIKey
BEZZFPOZAYTVHN-UHFFFAOYSA-N
Libraries
SPECMTS3, Spectrum_ED
Other recorded names
Oxfendazole
Stored SMILESCOC(=O)Nc1nc2cc(ccc2n1)S(=O)c1ccccc1

Matched external records: PubChem 40854

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

104 measurements across 104 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
ADORA2A · Adenosine receptor A2aChEMBLNo stored yeast mapping
Ido2 · Indoleamine 2,3-dioxygenase 2ChEMBLNo stored yeast mapping
TDP1 · Tyrosyl-DNA phosphodiesterase 1ChEMBLTDP1 YBR223C (ortholog_one2one)

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete OXFENDAZOLE research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.