CHEMGRID MOLECULE CARD
PROPRANOLOL HYDROCHLORIDE (+/-)
PROPRANOLOL HYDROCHLORIDE (+/-) in ChemGrid: 104 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01505270
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01505270
- Molecular formula
- C16ClH22NO2
- InChIKey
- ZMRUPTIKESYGQW-UHFFFAOYSA-N
- Libraries
- SPECMTS3, Spectrum_ED
- Other recorded names
- Propranolol Hydrochloride
Stored SMILES
Cl.CC(C)NCC(O)COc1cccc2ccccc12Matched external records: PubChem 62882
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
104 measurements across 104 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ADRB1 · Adrenergic receptor beta | ChEMBL | No stored yeast mapping |
| ADRB2 · Beta-2 adrenergic receptor | ChEMBL | No stored yeast mapping |
| HTR1A · 5-hydroxytryptamine receptor 1A | ChEMBL | No stored yeast mapping |
| HTR2A · 5-hydroxytryptamine receptor 2A | ChEMBL | No stored yeast mapping |
| HTR2C · 5-hydroxytryptamine receptor 2C | ChEMBL | No stored yeast mapping |
| HTR6 · 5-hydroxytryptamine receptor 6 | ChEMBL | No stored yeast mapping |
| SIGMAR1 · Sigma non-opioid intracellular receptor 1 | ChEMBL | No stored yeast mapping |
| TMEM97 · Sigma intracellular receptor 2 | ChEMBL | YLR050C (ortholog_one2one) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete PROPRANOLOL HYDROCHLORIDE (+/-) research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.