CHEMGRID MOLECULE CARD
ALFLUZOCIN
ALFLUZOCIN in ChemGrid: 192 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01505263
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01505263
- Molecular formula
- C19H27N5O4
- CAS registry number
- 81403-80-7
- InChIKey
- WNMJYKCGWZFFKR-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3
- Other recorded names
- Alfuzosin
Stored SMILES
COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C1CCCO1Matched external records: PubChem 2092
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
192 measurements across 192 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ACHE · Acetylcholinesterase | ChEMBL | No stored yeast mapping |
| ADRA1A · Adrenergic receptor alpha-1 | ChEMBL | No stored yeast mapping |
| Adra1a · Alpha-1A adrenergic receptor | ChEMBL | No stored yeast mapping |
| Adra1b · Alpha-1B adrenergic receptor | ChEMBL | No stored yeast mapping |
| Adra1d · Alpha-1D adrenergic receptor | ChEMBL | No stored yeast mapping |
| ADRA2C · Alpha-2C adrenergic receptor | ChEMBL | No stored yeast mapping |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL | SET2 YJL168C (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete ALFLUZOCIN research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.