CHEMGRID MOLECULE CARD
ROPINIROLE
ROPINIROLE in ChemGrid: 104 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01505178
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01505178
- Molecular formula
- C16H24N2O
- CAS registry number
- 91374-21-9
- InChIKey
- UHSKFQJFRQCDBE-UHFFFAOYSA-N
- Libraries
- SPECMTS3, Spectrum_ED
- Other recorded names
- Ropinirole
Stored SMILES
CCCN(CCC)CCc1cccc2NC(=O)Cc12Matched external records: PubChem 5095
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
104 measurements across 104 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Drd2 · D(2) dopamine receptor | ChEMBL | No stored yeast mapping |
| DRD2 · Dopamine receptor | ChEMBL | No stored yeast mapping |
| Drd3 · D(3) dopamine receptor | ChEMBL | No stored yeast mapping |
| DRD4 · D(4) dopamine receptor | ChEMBL | No stored yeast mapping |
| HTR1A · 5-hydroxytryptamine receptor 1A | ChEMBL | No stored yeast mapping |
| HTR2A · 5-hydroxytryptamine receptor 2A | ChEMBL | No stored yeast mapping |
| HTR2B · 5-hydroxytryptamine receptor 2B | ChEMBL | No stored yeast mapping |
| OPRK1 · Kappa-type opioid receptor | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete ROPINIROLE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.