CHEMGRID MOLECULE CARD
3-HYDROXYTYRAMINE
3-HYDROXYTYRAMINE in ChemGrid: 13 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01505155
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01505155
- Molecular formula
- C8H11NO2
- CAS registry number
- 62-31-7
- InChIKey
- VYFYYTLLBUKUHU-UHFFFAOYSA-N
- Libraries
- Spectrum_ED
- Other recorded names
- Dopamine
Stored SMILES
NCCc1ccc(O)c(O)c1Matched external records: PubChem 681
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
13 measurements across 13 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| DRD1 · D(1A) dopamine receptor | ChEMBL | No stored yeast mapping |
| DRD1 · Dopamine receptor | ChEMBL | No stored yeast mapping |
| DRD2 · D(2) dopamine receptor | ChEMBL | No stored yeast mapping |
| DRD3 · D(3) dopamine receptor | ChEMBL | No stored yeast mapping |
| Drd4 · D(4) dopamine receptor | ChEMBL | No stored yeast mapping |
| DRD5 · D(1B) dopamine receptor | ChEMBL | No stored yeast mapping |
| SLC6A2 · Sodium-dependent noradrenaline transporter | ChEMBL | No stored yeast mapping |
| ADRA2A · Alpha-2A adrenergic receptor | ChEMBL analogue | No stored yeast mapping |
| BLM · RecQ-like DNA helicase BLM | ChEMBL analogue | SGS1 YMR190C (ortholog_one2one) |
| DRD1 · D(1A) dopamine receptor | ChEMBL analogue | No stored yeast mapping |
| Drd2 · D(2) dopamine receptor | ChEMBL analogue | No stored yeast mapping |
| DRD3 · D(3) dopamine receptor | ChEMBL analogue | No stored yeast mapping |
| DRD4 · D(4) dopamine receptor | ChEMBL analogue | No stored yeast mapping |
| DRD5 · D(1B) dopamine receptor | ChEMBL analogue | No stored yeast mapping |
| GFER · FAD-linked sulfhydryl oxidase ALR | ChEMBL analogue | ERV1 YGR029W (ortholog_one2one) |
| MAPT · Microtubule-associated protein tau | ChEMBL analogue | No stored yeast mapping |
| RECQL · ATP-dependent DNA helicase Q1 | ChEMBL analogue | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL analogue | TDP1 YBR223C (ortholog_one2one) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 3-HYDROXYTYRAMINE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.