CHEMGRID MOLECULE CARD
2-AMINOETHYLDIPHENYL BORONATE
2-AMINOETHYLDIPHENYL BORONATE in ChemGrid: 104 screened assays, 64 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01505120
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01505120
- Molecular formula
- BC14H16NO
- CAS registry number
- 524-95-8
- InChIKey
- BLZVCIGGICSWIG-UHFFFAOYSA-N
- Libraries
- SPECMTS3, Spectrum_ED
- Other recorded names
- AMINOETHOXYDIPHENYLBORANE; 2-Aminoethoxydiphenyl borate
Stored SMILES
NCCOB(c1ccccc1)c1ccccc1Matched external records: PubChem 1598
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
104 measurements across 104 distinct library–species–strain assays; 64 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
| Strain | Library | Species identifier | Z-score |
|---|---|---|---|
| BY4743 | Spectrum_ED | 4932 | -76.49 |
| BY4741-3rd | Spectrum_ED | 4932 | -57.03 |
| BY4741-2nd | Spectrum_ED | 4932 | -51.02 |
| pep5 | SPECMTS3 | 4932 | -41.67 |
| BY4741 | SPECMTS3 | 4932 | -38.32 |
| lat1 | SPECMTS3 | 4932 | -37.01 |
| srl3 | SPECMTS3 | 4932 | -36.67 |
| drs2 | SPECMTS3 | 4932 | -36.55 |
| fet3 | SPECMTS3 | 4932 | -34.96 |
| MT2481-pdr1pdr3-2nd | SPECMTS3 | 4932 | -34.68 |
| hpr5 | SPECMTS3 | 4932 | -32.27 |
| paf1 | SPECMTS3 | 4932 | -31.36 |
Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ALOX12 · Polyunsaturated fatty acid lipoxygenase ALOX12 | ChEMBL | No stored yeast mapping |
| ALOX15 · Polyunsaturated fatty acid lipoxygenase ALOX15 | ChEMBL | No stored yeast mapping |
| ALOX15B · Polyunsaturated fatty acid lipoxygenase ALOX15B | ChEMBL | No stored yeast mapping |
| CYP1A2 · Cytochrome P450 1A2 | ChEMBL | No stored yeast mapping |
| CYP3A4 · Cytochrome P450 3A4 | ChEMBL | No stored yeast mapping |
| KDM4E · Lysine-specific demethylase 4E | ChEMBL | YJR119C (ortholog_one2many) |
| MAPK1 · Mitogen-activated protein kinase 1 | ChEMBL | SLT2 YHR030C (ortholog_many2many); YKL161C (ortholog_many2many) |
| Rorc · Nuclear receptor ROR-gamma | ChEMBL | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL | TDP1 YBR223C (ortholog_one2one) |
| TRPM2 · Transient receptor potential cation channel subfamily M member 2 | ChEMBL | No stored yeast mapping |
| Trpm7 · Transient receptor potential cation channel subfamily M member 7 | ChEMBL | No stored yeast mapping |
| VDR · Vitamin D3 receptor | ChEMBL | No stored yeast mapping |
| ALOX12 · Polyunsaturated fatty acid lipoxygenase ALOX12 | ChEMBL analogue | No stored yeast mapping |
| ALOX15 · Polyunsaturated fatty acid lipoxygenase ALOX15 | ChEMBL analogue | No stored yeast mapping |
| ALOX15B · Polyunsaturated fatty acid lipoxygenase ALOX15B | ChEMBL analogue | No stored yeast mapping |
| CYP1A2 · Cytochrome P450 1A2 | ChEMBL analogue | No stored yeast mapping |
| CYP3A4 · Cytochrome P450 3A4 | ChEMBL analogue | No stored yeast mapping |
| KDM4E · Lysine-specific demethylase 4E | ChEMBL analogue | YJR119C (ortholog_one2many) |
| MAPK1 · Mitogen-activated protein kinase 1 | ChEMBL analogue | SLT2 YHR030C (ortholog_many2many); YKL161C (ortholog_many2many) |
| Rorc · Nuclear receptor ROR-gamma | ChEMBL analogue | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL analogue | TDP1 YBR223C (ortholog_one2one) |
| TRPM2 · Transient receptor potential cation channel subfamily M member 2 | ChEMBL analogue | No stored yeast mapping |
| Trpm7 · Transient receptor potential cation channel subfamily M member 7 | ChEMBL analogue | No stored yeast mapping |
| VDR · Vitamin D3 receptor | ChEMBL analogue | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 2-AMINOETHYLDIPHENYL BORONATE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.