CHEMGRID MOLECULE CARD
PIRINIXIC ACID
PIRINIXIC ACID in ChemGrid: 91 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01505106
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01505106
- Molecular formula
- C14ClH14N3O2S
- CAS registry number
- 50892-23-4
- InChIKey
- SZRPDCCEHVWOJX-UHFFFAOYSA-N
- Libraries
- SPECMTS3
- Other recorded names
- Pirinixic Acid
Stored SMILES
Cc1cccc(Nc2cc(Cl)nc(SCC(O)=O)n2)c1CMatched external records: PubChem 5694
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
91 measurements across 91 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Akr1b1 · Aldo-keto reductase family 1 member B1 | ChEMBL | AAD3 YCR107W (ortholog_many2many); AAD4 YDL243C (ortholog_many2many); YPR1 YDR368W (ortholog_many2many); AAD10 YJR155W (ortholog_many2many); AAD14 YNL331C (ortholog_many2many); AAD15 YOL165C (ortholog_many2many); GCY1 YOR120W (ortholog_many2many) |
| CYP2D6 · Cytochrome P450 2D6 | ChEMBL | No stored yeast mapping |
| Ppara · Peroxisome proliferator-activated receptor alpha | ChEMBL | No stored yeast mapping |
| PPARD · Peroxisome proliferator-activated receptor delta | ChEMBL | No stored yeast mapping |
| PPARG · Peroxisome proliferator-activated receptor gamma | ChEMBL | No stored yeast mapping |
| RXRA · Retinoic acid receptor RXR-alpha | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete PIRINIXIC ACID research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.