CHEMGRID MOLECULE CARD
4-(3-BUTOXY-4-METHOXYBENZYL)IMIDAZOLIDIN-2-ONE
4-(3-BUTOXY-4-METHOXYBENZYL)IMIDAZOLIDIN-2-ONE in ChemGrid: 104 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01505104
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01505104
- Molecular formula
- C15H22N2O3
- CAS registry number
- 29925-17-5
- InChIKey
- PDMUULPVBYQBBK-UHFFFAOYSA-N
- Libraries
- SPECMTS3, Spectrum_ED
- Other recorded names
- 4-((3-Butoxy-4-methoxyphenyl)methyl)-2-imidazolidinone
Stored SMILES
CCCCOc1cc(CC2CNC(=O)N2)ccc1OCMatched external records: PubChem 5087
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
104 measurements across 104 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL | SET2 YJL168C (ortholog_many2many) |
| GLP1R · Glucagon-like peptide 1 receptor | ChEMBL | No stored yeast mapping |
| MAPK1 · Mitogen-activated protein kinase 1 | ChEMBL | SLT2 YHR030C (ortholog_many2many); YKL161C (ortholog_many2many) |
| PDE4A · 3',5'-cyclic-AMP phosphodiesterase 4A | ChEMBL | No stored yeast mapping |
| PDE4B · 3',5'-cyclic-AMP phosphodiesterase 4B | ChEMBL | No stored yeast mapping |
| Pde4d · Phosphodiesterase 4 | ChEMBL | No stored yeast mapping |
| POLI · DNA polymerase iota | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 4-(3-BUTOXY-4-METHOXYBENZYL)IMIDAZOLIDIN-2-ONE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.