CHEMGRID MOLECULE CARD
CARVEDILOL
CARVEDILOL in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01504257
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01504257
- Molecular formula
- C24H26N2O4
- CAS registry number
- 72956-09-3
- InChIKey
- OGHNVEJMJSYVRP-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3, Spectrum_ED
- Other recorded names
- Carvedilol
Stored SMILES
COc1ccccc1OCCNCC(O)COc1cccc2nc3ccccc3c21Matched external records: PubChem 2585
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Adrenergic receptor alpha-1 | ChEMBL | No stored yeast mapping |
| Adrenergic receptor alpha-2 | ChEMBL | No stored yeast mapping |
| ADRA1A · Alpha-1A adrenergic receptor [CHEMBL229] | ChEMBL | No stored yeast mapping |
| Adra1a · Alpha-1A adrenergic receptor [CHEMBL319] | ChEMBL | No stored yeast mapping |
| Adra1b · Alpha-1B adrenergic receptor | ChEMBL | No stored yeast mapping |
| ADRA1D · Alpha-1D adrenergic receptor | ChEMBL | No stored yeast mapping |
| ADRB1 · Beta-1 adrenergic receptor [CHEMBL213] | ChEMBL | No stored yeast mapping |
| Adrb1 · Beta-1 adrenergic receptor [CHEMBL3252] | ChEMBL | No stored yeast mapping |
| ADRB2 · Beta-2 adrenergic receptor | ChEMBL | No stored yeast mapping |
| ADRB3 · Beta-3 adrenergic receptor | ChEMBL | No stored yeast mapping |
| Htr1a · 5-hydroxytryptamine receptor 1A | ChEMBL | No stored yeast mapping |
| HTR2B · 5-hydroxytryptamine receptor 2B | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete CARVEDILOL research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.