CHEMGRID MOLECULE CARD
RHOIFOLIN
RHOIFOLIN in ChemGrid: 114 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01504075
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01504075
- Molecular formula
- C27H30O14
- CAS registry number
- 17306-46-6
- InChIKey
- RPMNUQRUHXIGHK-UHFFFAOYSA-N
- Libraries
- Spectrum, Spectrum_ED
- Other recorded names
- Npc131482
Stored SMILES
CC1OC(OC2C(O)C(O)C(CO)OC2Oc2cc(O)c3C(=O)C=C(Oc3c2)c2ccc(O)cc2)C(O)C(O)C1OMatched external records: PubChem 5459217
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
114 measurements across 114 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ATAD5 · ATPase family AAA domain-containing protein 5 | ChEMBL analogue | No stored yeast mapping |
| FEN1 · Flap endonuclease 1 | ChEMBL analogue | RAD27 YKL113C (ortholog_one2one) |
| PIN1 · Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | ChEMBL analogue | ESS1 YJR017C (ortholog_one2one) |
| POLH · DNA polymerase eta | ChEMBL analogue | RAD30 YDR419W (ortholog_one2one) |
| POLI · DNA polymerase iota | ChEMBL analogue | No stored yeast mapping |
| POLK · DNA polymerase kappa | ChEMBL analogue | TRF5 YNL299W (ortholog_many2many); PAP2 YOL115W (ortholog_many2many) |
| VDR · Vitamin D3 receptor | ChEMBL analogue | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete RHOIFOLIN research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.