CHEMGRID MOLECULE CARD
FLUTRIMAZOLE
FLUTRIMAZOLE in ChemGrid: 101 screened assays, 100 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01503945
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01503945
- Molecular formula
- C22F2H16N2
- InChIKey
- QHMWCHQXCUNUAK-UHFFFAOYSA-N
- Libraries
- Spectrum
- Other recorded names
- Flutrimazole
Stored SMILES
Fc1ccc(cc1)C(n1ccnc1)(c1ccccc1)c1ccccc1FMatched external records: PubChem 3401
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
101 measurements across 101 distinct library–species–strain assays; 100 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
| Strain | Library | Species identifier | Z-score |
|---|---|---|---|
| elg1 | Spectrum | 4932 | -57.91 |
| nup100 | Spectrum | 4932 | -56.10 |
| tub3 | Spectrum | 4932 | -54.83 |
| pex11 | Spectrum | 4932 | -54.47 |
| set2 | Spectrum | 4932 | -53.72 |
| mad1 | Spectrum | 4932 | -53.42 |
| CIN2 | Spectrum | 4932 | -52.73 |
| clb2 | Spectrum | 4932 | -52.48 |
| LCB3 | Spectrum | 4932 | -51.62 |
| rvs167 | Spectrum | 4932 | -51.25 |
| CIN8 | Spectrum | 4932 | -51.10 |
| KRE1 | Spectrum | 4932 | -51.03 |
Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ADORA3 · Adenosine receptor A3 | ChEMBL | No stored yeast mapping |
| CCKBR · Gastrin/cholecystokinin type B receptor | ChEMBL | No stored yeast mapping |
| HDAC6 · Protein deacetylase HDAC6 | ChEMBL | HDA1 YNL021W (ortholog_one2one) |
| KCNH2 · Voltage-gated inwardly rectifying potassium channel KCNH2 | ChEMBL | No stored yeast mapping |
| MLNR · Motilin receptor | ChEMBL | No stored yeast mapping |
| NR1H4 · Bile acid receptor | ChEMBL | No stored yeast mapping |
| NR1I2 · Nuclear receptor subfamily 1 group I member 2 | ChEMBL | No stored yeast mapping |
| OPRK1 · Kappa-type opioid receptor | ChEMBL | No stored yeast mapping |
| rep · Replicase polyprotein 1ab | ChEMBL | No stored yeast mapping |
| SLC6A3 · Sodium-dependent dopamine transporter | ChEMBL | No stored yeast mapping |
| TBXA2R · Thromboxane A2 receptor | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete FLUTRIMAZOLE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.