ChemGrid

CHEMGRID MOLECULE CARD

RIBAVIRIN

RIBAVIRIN in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01503938

Explore activity & SONAR
Chemical structure of RIBAVIRIN
Stored molecular structure
205Screened assays
0Significant assay responses
6Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE01503938
Molecular formula
C8H12N4O5
CAS registry number
36791-04-5
InChIKey
IWUCXVSUMQZMFG-UHFFFAOYSA-N
Libraries
Spectrum, SPECMTS3, Spectrum_ED
Other recorded names
1-Pentofuranosyl-1H-1,2,4-triazole-3-carboxamide
Stored SMILESNC(=O)c1ncn(n1)C1OC(CO)C(O)C1O

Matched external records: PubChem 5064

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
ffp · 4'-phosphopantetheinyl transferase ffpChEMBLNo stored yeast mapping
LMNA · Prelamin-A/CChEMBLNo stored yeast mapping
SMN1 · Survival motor neuron proteinChEMBLNo stored yeast mapping
ffp · 4'-phosphopantetheinyl transferase ffpChEMBL analogueNo stored yeast mapping
LMNA · Prelamin-A/CChEMBL analogueNo stored yeast mapping
SMN1 · Survival motor neuron proteinChEMBL analogueNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete RIBAVIRIN research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.