CHEMGRID MOLECULE CARD
CELECOXIB
CELECOXIB in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01503678
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01503678
- Molecular formula
- C17F3H14N3O2S
- CAS registry number
- 169590-42-5
- InChIKey
- RZEKVGVHFLEQIL-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3, Spectrum_ED
- Other recorded names
- Celecoxib
Stored SMILES
Cc1ccc(cc1)c1cc(nn1c1ccc(cc1)S(N)(=O)=O)C(F)(F)FMatched external records: PubChem 2662
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Carbonate dehydratase | ChEMBL | No stored yeast mapping |
| CA · Alpha carbonic anhydrase | ChEMBL | No stored yeast mapping |
| CA12 · Carbonic anhydrase 12 | ChEMBL | No stored yeast mapping |
| CA2 · Carbonic anhydrase 2 | ChEMBL | No stored yeast mapping |
| CA9 · Carbonic anhydrase 9 | ChEMBL | No stored yeast mapping |
| MT-CO2 · Cytochrome c oxidase subunit 2 | ChEMBL | COX2 Q0250 (ortholog_one2one) |
| PTGS1 · Prostaglandin G/H synthase 1 | ChEMBL | No stored yeast mapping |
| PTGS2 · Prostaglandin G/H synthase 2 | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete CELECOXIB research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.