CHEMGRID MOLECULE CARD
MENTHOL(-)
MENTHOL(-) in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01503134
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01503134
- Molecular formula
- C10H20O
- CAS registry number
- 1490-04-6
- InChIKey
- NOOLISFMXDJSKH-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3, Spectrum_ED
- Other recorded names
- (-)-MENTHOL; (-)-Menthol; Menthol
Stored SMILES
CC(C)C1CCC(C)CC1OMatched external records: PubChem 16666 PubChem 1254
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| NR1H4 · Bile acid receptor | ChEMBL | No stored yeast mapping |
| OR5K1 · Olfactory receptor 5K1 | ChEMBL | No stored yeast mapping |
| PTGS2 · Prostaglandin G/H synthase 2 | ChEMBL | No stored yeast mapping |
| RUNX1 · Runt-related transcription factor 1/Core-binding factor subunit beta | ChEMBL | No stored yeast mapping |
| TRPA1 · Transient receptor potential cation channel subfamily A member 1 | ChEMBL | No stored yeast mapping |
| TRPM8 · Transient receptor potential cation channel subfamily M member 8 | ChEMBL | No stored yeast mapping |
| Trpm8 · Transient receptor potential cation channel subfamily M member 8 | ChEMBL | No stored yeast mapping |
| VDR · Vitamin D3 receptor | ChEMBL | No stored yeast mapping |
| Aminopeptidase | ChEMBL analogue | No stored yeast mapping |
| ALDH1A1 · Aldehyde dehydrogenase 1A1 | ChEMBL analogue | ALD5 YER073W (ortholog_many2many); ALD3 YMR169C (ortholog_many2many); ALD2 YMR170C (ortholog_many2many); ALD4 YOR374W (ortholog_many2many); ALD6 YPL061W (ortholog_many2many) |
| FTL · Ferritin light chain | ChEMBL analogue | No stored yeast mapping |
| HDAC6 · Protein deacetylase HDAC6 | ChEMBL analogue | HDA1 YNL021W (ortholog_one2one) |
| rep · Replicase polyprotein 1ab | ChEMBL analogue | No stored yeast mapping |
| USP1 · Ubiquitin carboxyl-terminal hydrolase 1 | ChEMBL analogue | UBP13 YBL067C (ortholog_many2many); UBP9 YER098W (ortholog_many2many); UBP8 YMR223W (ortholog_many2many); UBP2 YOR124C (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete MENTHOL(-) research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.